BACKGROUND We studied the transmission of rotavirus infection in households in peri-urban Ecuador in the vaccination era. METHODS Stool samples were collected from household contacts of child rotavirus cases, diarrhea controls and healthy controls following presentation of the index child to health facilities. Rotavirus infection status of contacts was determined by RT-qPCR. We examined facto...

Rotavirus infections were detected in 210 of 675 children with acute diarrhea admitted to a major pediatric hospital in Rome from January 1982 through December 1985. Most of the patients with rotavirus infections were admitted during the winter season in both 1982 and 1985, whereas during the two intermediate years, cases occurred in all months. Among 84 rotavirus samples examined, 14 different...

Background Rotaviruses are the primary cause of acute gastroenteritis in young children worldwide and a significant proportion of these infections occur in Africa. Objectives In the present study, we determined the prevalence and risk factors of rotavirus infection among children younger than age 5 years with or without diarrhoea in Calabar, Nigeria, using a rapid point-of-care test. Method...

Infectious diarrhea is endemic in most developing countries. We aimed to investigate the protozoan, viral, and bacterial causes of acute diarrhea in Taif, Saudi Arabia. A cross-sectional prospective 1-year study was conducted on 163 diarrheal patients of various ages. Stool samples were collected, 1 per patient, and tested for 3 protozoa, 3 viruses, and 9 bacteria with the Luminex Gastrointesti...

BACKGROUND Current, nationally representative data on rotavirus disease burden and rotavirus strains in India are needed to understand the potential health benefits of rotavirus vaccination. METHODS The Indian Rotavirus Strain Surveillance Network was established with 4 laboratories and 10 hospitals in 7 different regions of India. At each hospital, children aged <5 years who presented with a...

Rotavirus exists throughout the world and is estimated to have infected every individual by their fifth birthday. For this reason, there has been a significant drive for the development of a vaccination for the virus. After much failure, Rotashield, a tetravalent rhesus-based live attenuated vaccine was developed and approved in 1998. Following over 1.5 million administrations, it was suspended...

PURPOSE The aim of the study was to establish the main etiologic agents of acute viral gastroenteritis and to asses the severity of illness associated with the different viral agents of gastroenteritis in children hospitalized during spring/summer season 2008. MATERIAL AND METHODS 181 stool specimens were collected from children under 5 years of age, hospitalized with acute viral diarrhea fro...

1. Kapikian AZ, Chanock RM. Rotaviruses. In: Fields BN Knipe DM Howley PM, editors. Fields Virology. 3 ed. Philadelphia: Lippincott-Raven, 1996:1657-1708. 2. Bishop RF. Natural history of human rotavirus infections. In: Kapikian AZ (ed). Viral infections of the gastrointestinal tract. 2nd ed. Marcel Dekker, New York, 1994:131-167. 3. Carlin JB, Chondros P, Masendycz P, Bugg H, Bishop RF, Barnes...

In this study, the diversity of G and P genotypes of rotavirus strains in Burkinabe children were examined. Between November 2008 and February 2010, 447 stool samples were collected from children <5 years of age with acute diarrhea visiting hospital in Ouagadougou. Group A rotavirus was previously detected in 151/447 (33.8%) of the samples tested by an immunochromatographic test and these sampl...

BACKGROUND Rotavirus is the major cause of acute gastroenteritis and severe dehydrating diarrhea in young children. METHODS To estimate the proportion of hospital admissions for rotavirus acute gastroenteritis and identify the circulating G and P genotypes among children under five years of age, we conducted a prospective observational study from January to December 2008, recruiting children ...