Rosacea is a common cutaneous disorder affecting the face. It is more frequently encountered in fairskinned races and in females. The aetiology is unknown. The treatment of rosacea can be difficult and includes topical treatments like benzoyl peroxide, clindamycin and metronidazole as well as systemic treatments like retinoids. We present three cases of rosacea treated homeopathically. They all...

Sir, Rosacea and chronic urticaria are two common dermatological conditions that have been associated with Helicobacter pylori infection (1). Several reports have described improvement in the dermatological condition following administration of antimicrobial therapy to eradicate H. pylori (2 ± 4). However, recent controlled reports have found similar rates of H. pylori infection in patients wit...

Topical calcineurin inhibitors have been used outside their approved indications for a number of conditions, including topical steroid-induced rosacea. However, tacrolimus ointment itself has been reported to trigger rosacea in a small number of cases. We report a case of a rosacea-like eruption in a 39-year-old woman occurring after the use of pimecrolimus cream for 12 months for atopic dermat...

Rosacea is a common chronic skin condition that displays a broad diversity of clinical manifestations. Although the pathophysiological mechanisms of the four subtypes are not completely elucidated, the key elements often present are augmented immune responses of the innate and adaptive immune system, and neurovascular dysregulation. The most common primary feature of all cutaneous subtypes of r...

BACKGROUND Although rosacea is a chronic cutaneous inflammatory disorder that's commonly seen in adults, the etiology and pathogenesis of the illness remain unclear. A well established diagnostic classification and grading system may play a critical role in performing research and it would serve as a diagnostic reference in the clinical field. OBJECTIVE We sought to classify the patients with...

BACKGROUND Patients with papulopustular rosacea have a higher density of Demodex folliculorum mites on their faces than normal subjects but the role, if any, of their mites in initiating inflammation is disputed. Selective antibiotics are effective in reducing the inflammatory changes of papulopustular rosacea, but their mode of action is unknown. OBJECTIVES To investigate whether a D. follic...

Rosacea is a common and chronic inflammatory skin disease most frequently seen in groups of genetically related individuals. Although the symptoms of rosacea are heterogeneous, they are all related by the presence of characteristic facial or ocular inflammation involving both the vascular and tissue stroma. Until recently, the pathophysiology of this disease was limited to descriptions of a wid...

Rosacea is relatively common, typically occurring in individuals of Northern European and Celtic origin between 30 and 50 years of age. It is more common in women, but may be more severe in men. Currently there is no cure available for rosacea, but it can be controlled with topical and oral drug therapy. Topical metronidazole 1% cream is approved by the US FDA for the treatment of inflammatory ...

I n the most recent issue of this publication, we provided an overview of current classifications and grading systems that define rosacea, along with information on traditional therapeutic approaches for the management of inflammatory papules and pustules. In this issue, we’ll focus on ivermectin 1%, the newest addition to the rosacea armamentarium, by reviewing its mechanism of action and expl...

Rosacea is a common, chronic inflammatory skin disease that can present with a variety of signs and symptoms. The potentially simultaneous occurrence of different signs and symptoms is due to different underlying inflammatory pathways, emphasizing the need for complementary treatment approaches. Topical ivermectin cream (10 mg/g) and systemic, oral anti-inflammatory doxycycline (40 mg modified-...