a disorder that is generally restricted to infants weighing less than 1001 g at birth. The size of the surviving population of infants with ROP dwarfs all previous predictions of absolute numbers because survival rates of infants weighing 501-750 g at birth are now approaching 60%, and those of infants weighing 751-1000 g are now approaching 90%. The total incidence of ROP in infants weighing 5...

This study was designed to determine the frequency of retinopathy of prematurity (ROP) and the effectiveness of the screening protocol in preterm infants for our country. With these objectives, the charts of 1000 preterm infants were reviewed in Ondokuz Mayis University, Department of Ophthalmology. ROP frequency, the effect of gestational age (GA) and birth weight (BW) and the effectiveness of...

Purpose To describe the efficacy of intravitreal bevacizumab for the treatment of type 1 retinopathy of prematurity (ROP) in zone I. Methods Preterm infants with type 1 ROP in zone I (zone I ROP, any stage with plus disease or zone I ROP, stage 3 without plus disease) were enrolled in this prospective study. Intravitreal bevacizumab (0.625 mg/0.025 ml) was injected under topical anesthesia. P...

To investigate the incidence of Retinopathy of Prematurity (ROP) in Beijing, North China, and to evaluate the effectiveness of different ROP screening criteria, we conducted a prospective cohort study in a single-neonatal intensive care unit (NICU). A total of 2997 premature infants with birth weight (BW) ≤ 2000 g and/or gestational age (GA) ≤ 34 weeks had completed ROP screening. ROP was diagn...

The two commonly used plasmid vectors, pBR322 and pUC19, are both derivatives of the parent plasmid, pColE-1. However, it has been observed that pBR322 is excluded from the host cells following co-transformation of pBR322 and pUC19. One potential explanation for this exclusion effect is the presence of a functional rop gene in pBR322. The rop gene encodes for a protein that stabilizes the inter...

PURPOSE To compare the frequency and severity of retinopathy of prematurity (ROP) among singleton and multiple-birth neonates referred to Farabi Eye Hospital, Tehran- Iran. METHODS In this retrospective study, records of 99 consecutive neonates from multiplegestation pregnancies including 68 twins, 26 triplets and 5 quadruplets who were screened for ROP from 2002 to 2004 were reviewed. The fr...

OBJECTIVE To determine the incidence and severity of Retinopathy of Prematurity (ROP) in the Murcia region of Spain. METHODS This was a retrospective study of all infants born preterm in the Murcia region during 2004, who were screened for ROP. Our screening criteria were: Infants with a gestational age <or= 32 weeks (GA) or with a birth weight <or= 1500 g (BW). We evaluated sex, GA, BW, pari...

OBJECTIVE To prospectively measure accuracy, reliability, and image quality of telemedical retinopathy of prematurity (ROP) diagnosis. METHODS Two-hundred forty-eight eyes from 67 consecutive infants underwent wide-angle retinal imaging by a trained neonatal nurse at 31 to 33 weeks' and/or 35 to 37 weeks' postmenstrual age (PMA) using a standard protocol. Data were uploaded to a Web-based tel...

BACKGROUND/AIM Retinopathy of prematurity (ROP) is a multifactorial disease in premature infants. The aim of this study was to determine the incidence of ROP in children treated at the Center of Neonatology, Pediatric Clinic, Clinical Center in Kragujevac, Serbia. METHODS The study covered all children with birth weight below 2,000 g and/or gestational age below the 37th week, who from June 2...