OBJECTIVES Genital infection with certain types of human papillomavirus (HPV) is the most important risk factor for cervical cancer. The male sexual partner is supposed to be the vector of the infection. However, the knowledge of risk factors for genital HPV DNA in men is limited. The objective of this paper is to study the risk factors for HPV infection in men and to compare them with those fo...

BACKGROUND High-risk human papillomavirus (HPV) is an oncogenic virus that causes oropharyngeal cancers, and it has a favorable outcome after the treatment. Unlike in oropharyngeal cancer, the prevalence and role of high-risk HPV in the etiology of hypopharyngeal squamous cell carcinoma (HPSCC) is uncertain. OBJECTIVE The aim of the present study was to evaluate the effect and prognostic sign...

Background and Purpose: a substantial number of studies have reported evidence on the involvement of human papillomaviruses (HPV) in oral and sinonasal papillomas and carcinomas. Oncogenic HPV subtypes 16 and 18 seem to play an important role in carcinogenesis, whereas low risk HPV subtypes 6 and 11 are usually characteristic of benign lesions. The aim of the present study was to evaluate a rol...

Cervical carcinoma is a leading cause of mortality from cancer among women worldwide. Oncogenic types of human papillomavirus (HPV) are recognised as causative agents of cervical cancer and its precursor, cervical intraepithelial neoplasia (CIN). It was shown that successful treatment of CIN results in clearance of HPV infection and treatment failure is accompanied by the detection of viral per...

BACKGROUND The prevalence, incidence and persistence of human papillomavirus (HPV) types in sub-Saharan Africa are not well established. The objectives of the current study are to describe (predictors of) the epidemiology of HPV among high-risk women in Kigali, Rwanda. METHODS HIV-negative, high-risk women were seen quarterly for one year, and once in Year 2. HIV serostatus, clinical, and beh...

BACKGROUND Chile has broad variations in weather, economics and population from the far desert north (Region 1) to the cold, icy south (Region 12). A home-based self-collected vaginal sampling was nested in the 2003 Chilean population-based health survey in order to explore the possibility of a type-specific geographical variation for human papillomavirus METHODS The population was a national...

The HPV-Risk assay is a novel real-time PCR assay targeting the E7 region of 15 high-risk human papillomavirus (HPV) types (i.e., HPV16, -18, -31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -66, -67, and -68), and provides additional genotype information for HPV16 and HPV18. This study evaluated the clinical performance and reproducibility of the HPV-Risk assay with cervical scraping specimen...

BACKGROUND AND OBJECTIVES Human papillomavirus (HPV) is the primary cause of cervical, anal, and other anogenital cancers, but risk factors for penile HPV detection in men have not been well-characterized. GOAL The goal of this study was to identify correlates of penile HPV detection in ethnically diverse men attending a sexually transmitted disease clinic. STUDY A cross-sectional investiga...

High-risk Human Papillomavirus (HPV) infections have recently emerged as an independent risk factor in head and neck squamous cell carcinoma (HNSCC). There has been a marked increase the incidence of HPV-induced HNSCC subtype, which demonstrates different genetics with better treatment outcome. Despite favourable prognosis HPV-HNSCC, modality, consisting high dose radiotherapy (RT) combination ...

Whether antibodies to human papillomavirus (HPV) capsids, elicited by natural infection, are protective is unknown. This question was addressed in a population-based cohort of 7046 women in Costa Rica by examining the association between baseline seroreactivity to HPV-16, HPV-18, or HPV-31 virus-like particles and the risk of subsequent HPV infection at a follow-up visit 5-7 years after enrollm...