There is a widening recognition that cancer cells are products of complex developmental processes. Carcinogenesis and metastasis formation are increasingly described as systems-level, network phenomena. Here we propose that malignant transformation is a two-phase process, where an initial increase of system plasticity is followed by a decrease of plasticity at late stages of carcinogenesis as a...

background: the interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries. objective: to understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from c...

STATEMENT OF PROBLEM The process of removing excess cement from subgingival margins after cementation of restorations to implant abutments may lead to scratching of the abutments or incomplete cement removal. PURPOSE The purpose of this study was to investigate and to compare the surfaces of abutments after the removal of three cements (glass ionomer, resin, and zinc phosphate) by use of thre...

An ultrasonic reflected wave at oblique incidence by porous medium with rigid frames is considered using equivalent fluid model. The viscous and thermal losses of the medium are described by two susceptibility kernels which depend on the viscous and thermal characteristic lengths. Analytical derivation of reflection coefficient is given in frequency domain. The simulated reflected wave is obtai...

A flexible-joint robot manipulator is a complex system because it is nonlinear, multivariable, highly coupled along with joint flexibility and uncertainty. To overcome flexibility, several methods have been proposed based on flexible model. This paper presents a novel method for controlling flexible-joint robot manipulators. A novel control law is presented by compensating flexibility to form a...

The article deals with a method for analysing slender masonry columns. proposed uses material and geometric non-linearity. Various stress-strain diagrams can be used: linear, linear-plastic, parabolic-plastic, two various parabolic rigid-plastic. In all cases, the tensile strength is neglected. used column in accordance Eurocodes ways: SLS (serviceability limit state) ULS (ultimate state). inte...

The onset of plastic yielding in a spherical shell loaded by a rigid flat is analyzed using finite element analysis. The effect of spherical shell geometry and material properties on the critical normal load, critical interference, and critical contact area, at the onset of plastic yielding, is investigated and the location where plastic yielding first occurs is determined. A universal dimensio...

A triangular mixed finite element model for the elasto-plastic analysis of Kirchhoff plates is presented. The proposed discretization is based on rigid in bending elements connected by means of rotational springs between the inter-element sides and constant bending moments on the influence area of each node. The continuity of the normal bending moment through the sides allows a standard Helling...