We present a novel automated method for assessment of image alignment, applied to non-rigid registration of brain Magnetic Resonance Imaging data (MRI) for image-guided neurosurgery. We propose a number of robust modifications to the Hausdorff distance (HD) metric, and apply it to the edges recovered from the brain MRI to evaluate the accuracy of image alignment. The evaluation results on synth...

The introduction of hybrid scanners has greatly increased the popularity of molecular imaging techniques. Many clinical applications benefit from combining complementary information based on the precise alignment of the two modalities. In case the alignment is inaccurate, then this crucial assumption often made for subsequent processing steps will be violated. However, this violation may not be...

In this thesis we are concerned with the geometric matching of shapes. We consider the local and rigid alignment of point clouds and the reconstruction of ruled surfaces from point clouds within an active shape framework. The emerging nonlinear and occasionally non-smooth optimization problems center around minimizations of the squared and unsigned distance function, respectively. Several appli...

It has been reported that non-articulatory visual cues to prosody tend to align with auditory cues, emphasizing auditory events that are in close alignment (visual alignment hypothesis). We investigated the temporal relationship between visual and auditory prosodic cues in a large corpus of utterances to determine the extent to which non-articulatory visual prosodic cues align with auditory one...

Abstract We formulate an active-gel theory for multicellular migration in the extra-cellular matrix (ECM). The cells are modeled as active, polar solvent, and ECM a viscoelastic solid. Our enables to analyze dynamic reciprocity between migrating their environment terms of distinct relative forces alignment mechanisms. linear stability homogeneously ECM. predicts that, consequence cell-matrix al...

This paper presents two new expressions for estimating registration accuracy in point-based rigid-body registration and points out a danger in using the traditional measure of registration accuracy. Rigid-body registration is appropriate for applications in which relatively rigid parts of the body are involved. In some such applications rigid-body registration is accomplished by aligning two se...

There continue to be increasing occurrences of both atomistic structure models in the PDB (possibly reconstructed from X-ray diffraction or NMR data), and 3D reconstructed cryo-electron microscopy (3D EM) maps (albeit at coarser resolution) of the same or homologous molecule or molecular assembly, deposited in the EMDB. To obtain the best possible structural model of the molecule at the best ac...

There continue to be increasing occurrences of both atomistic structure models in the PDB (possibly reconstructed from X-ray diffraction or NMR data), and 3D reconstructed cryo-electron microscopy (3D EM) maps (albeit at coarser resolution) of the same or homologous molecule or molecular assembly, deposited in the EMDB. To obtain the best possible structural model of the molecule at the best ac...

We describe a simple modification to a rigid endoscope so as to provide both high-quality conventional and confocal images of reasonably accessible regions of the body. This versatile system uses a structured illumination approach together with a conventional incoherent illumination source. Images taken in fluorescence are presented using this combined conventional and confocal endoscope.

In this paper we investigate extending the gradient-based inverse compositional image alignment method described by Baker and Matthews [1] by formulating the alignment process probabilistically using Bayes rule to obtain a posterior estimate of the alignment. The probabilistic formulation makes use of prior statistical information on the aligning function parameters, and we investigate the use ...