نتایج جستجو برای: rich repeat lrr
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Plant disease resistance is often mediated by nucleotide binding-leucine rich repeat (NLR) proteins which remain auto-inhibited until recognition of specific pathogen-derived molecules causes their activation, triggering a rapid, localized cell death called a hypersensitive response (HR). Three domains are recognized in one of the major classes of NLR proteins: a coiled-coil (CC), a nucleotide ...
Plants recruit innate immune receptors such as leucine-rich repeat (LRR) proteins to recognize pathogen attack and activate defense genes. Here, we identified the pepper (Capsicum annuum) pathogenesis-related protein10 (PR10) as a leucine-rich repeat protein1 (LRR1)-interacting partner. Bimolecular fluorescence complementation and coimmunoprecipitation assays confirmed the specific interaction ...
Plants utilize proteins containing nucleotide binding site (NB) and leucine-rich repeat (LRR) domains as intracellular innate immune receptors to recognize pathogens and initiate defense responses. Since mis-activation of defense responses can lead to tissue damage and even developmental arrest, proper regulation of NB-LRR protein signaling is critical. RAR1, SGT1, and HSP90 act as regulatory c...
Longan (Dimocarpus longan Lour.), an important subtropical fruit in the family Sapindaceae, is grown in more than 10 countries. Longan is an edible drupe fruit and a source of traditional medicine with polyphenol-rich traits. Tree size, alternate bearing, and witches' broom disease still pose serious problems. To gain insights into the genomic basis of longan traits, a draft genome sequence was...
Brown planthopper (BPH) has become the most devastating insect pests of rice and a serious threat to production. To combat newly occurring virulent BPH populations, it is still urgent explore more new broad-spectrum resistance genes integrate them into cultivars. In present study, we explored genetic basis in IRGC 8678. We identified mapped gene Bph43 region ~380 kb on chromosome 11. Genes enco...
Objectives: Capping protein Arp2/3 and myosin-I linker 1 (CARMIL1) encoded by the CARMIL, is a major, multidomain, membrane-linked regulating actin assembly; however, its function in inflammatory signaling not fully elucidated. The leucine-rich repeat (LRR) region of CARMIL1 has been associated with interleukin (IL)-1 receptor-associated kinase (IRAK) fibroblasts many methods including tandem m...
Instead of the immunoglobulin-type antigen receptors of jawed vertebrates, jawless fish have variable lymphocyte receptors (VLRs), which consist of leucine-rich repeat (LRR) modules. Somatic diversification of the VLR gene is shown here to occur through a multistep assembly of LRR modules randomly selected from a large bank of flanking cassettes. The predicted concave surface of the VLR is line...
Brassinosteroids regulate plant growth and development through a protein complex that includes the leucine-rich repeat receptor-like protein kinase (LRR-RLK) brassinosteroid-insensitive 1 (BRI1). Activation tagging was used to identify a dominant genetic suppressor of bri1, bak1-1D (bri1-associated receptor kinase 1-1Dominant), which encodes an LRR-RLK, distinct from BRI1. Overexpression of BAK...
Leucine-rich repeat (LRR)-containing 3B (LRRC3B) is a putative LRR-containing transmembrane protein and was down-regulated in many types of tumors. However, its expression and role in bladder cancer (BC) remains unclear. In our research, we aimed to assess the expression and function of LRRC3B in BC. Our results showed that the expression of LRRC3B was significantly reduced in BC cell lines. Th...
In Drosophila embryos and larvae, a small number of identified motor neurons innervate body wall muscles in a highly stereotyped pattern. Although genetic screens have identified many proteins that are required for axon guidance and synaptogenesis in this system, little is known about the mechanisms by which muscle fibers are defined as targets for specific motor axons. To identify potential ta...
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