MOTIVATION Many biological processes, such as cell cycle, circadian clock, menstrual cycles, are governed by oscillatory systems consisting of numerous components that exhibit rhythmic patterns over time. It is not always easy to identify such rhythmic components. For example, it is a challenging problem to identify circadian genes in a given tissue using time-course gene expression data. There...

OBJECTIVE This study was designed to determine the prevalence of rhythmic coma patterns in comatose children and to ascertain the prognostic significance of reactive rhythmic coma patterns. METHODS We retrospectively analyzed and classified electroencephalogram (EEGs) in comatose children between two months and 18 years of age during the period 1996 - 2003 according to modified Young's classi...

The mammalian circadian clock coordinates physiology with environmental cycles through the regulation of daily oscillations of gene expression. Thousands of transcripts exhibit rhythmic accumulations across mouse tissues, as determined by the balance of their synthesis and degradation. While diurnally rhythmic transcription regulation is well studied and often thought to be the main factor gene...

Rhythmic patterns are an important structural element in music. This paper investigates the use of rhythmic pattern modeling to infer metrical structure in musical audio recordings. We present a Hidden Markov Model (HMM) based system that simultaneously extracts beats, downbeats, tempo, meter, and rhythmic patterns. Our model builds upon the basic structure proposed by Whiteley et. al [20], whi...

In prior work (Corriveau et al., 2007), we showed that children with speech and language impairments (SLI) were significantly less sensitive than controls to two auditory cues to rhythmic timing, amplitude envelope rise time and duration. Here we explore whether rhythmic problems extend to rhythmic motor entrainment. Tapping in synchrony with a beat has been described as the simplest rhythmic a...