We describe a procedure for determining cefuroxime concentrations in serum by using high-performance liquid chromatography. The drug is extracted from serum with dimethylformamide and separated from other substances in the extract by reversed-phase chromatography. The ultraviolet (280-nm) absorption of the effluent was monitored and quantitated based on the height of the cefuroxime peak. Intra-...

styrene is an important constituent of widely used organic solvents in industries for production of various synthetic materials. the use of solid-phase extraction (spe) has grown and is a fertile technique of sample preparation as it provides better results than those produced by liquidliquid extraction. in this study, spe has been optimized, regarding sample ph, sample concentration, sample fl...

Biologically active peptides are of particular interest in food science and human nutrition because they have been shown to play several physiological roles. In vitro gastrointestinal digestion of lentil and whey proteins in this study produced high angiotensin-I converting enzyme inhibitory activity with 75.5±1.9 and 91.4±2.3% inhibition, respectively. High ACE inhibitory activity was observed...

New non-steroidal estrogen-receptor antagonists, R1 128 A, B, C and D, were isolated from the cultured broth of Streptomyces sp. No. 1 128 by solvent extraction, silica gel chromatography, reverse phase chromatography and preparative HPLC. These compounds inhibited estrogen binding to its receptor. The IC50 values of R1 128 A, B, C and D for partially purified rat uterine cytosol receptor were ...