Researchers have retrospectively analyzed the training intensity distribution (TID) of nationally and internationally competitive athletes in different endurance disciplines to determine the optimal volume and intensity for maximal adaptation. The majority of studies present a "pyramidal" TID with a high proportion of high volume, low intensity training (HVLIT). Some world-class athletes appear...

recurrent vulvovaginal candidiasis (rvvc) is seen in 5% of women with candida vaginitis. use of fluconazole as prophylactic treatment has been suggested for rvvc. the aim of the present study was to evaluate the efficacy of fluconazole suppressive therapy in rvvc patients, as a randomized, placebo-controlled, double-blind prophylactic study. among the 330 women with acute symptomatic vulvovagin...