نتایج جستجو برای: restriction modification system

تعداد نتایج: 2396706  

Journal: :Genetics and Molecular Biology 2007

2016
Awais Anjum Kelly J. Brathwaite Jack Aidley Phillippa L. Connerton Nicola J. Cummings Julian Parkhill Ian Connerton Christopher D. Bayliss

Phase-variable restriction-modification systems are a feature of a diverse range of bacterial species. Stochastic, reversible switches in expression of the methyltransferase produces variation in methylation of specific sequences. Phase-variable methylation by both Type I and Type III methyltransferases is associated with altered gene expression and phenotypic variation. One phase-variable gene...

Journal: :Nucleic acids research 1986
P R Whitehead D Jacobs N L Brown

We describe the partial purification and characterisation of five Type II restriction endonucleases from two strains of Herpetosiphon giganteus. One of the activities, HgiJII, was the first enzyme found that cleaves DNA at the family of related sequences 5'-G-R-G-C-Y/C-3'. This enzyme may be related to the enzyme HgiAI from a different strain of the same species, and which cleaves at the sites ...

2016
Sebastian Bubendorfer Juliane Krebes Ines Yang Elias Hage Thomas F Schulz Christelle Bahlawane Xavier Didelot Sebastian Suerbaum

Recombination plays a dominant role in the evolution of the bacterial pathogen Helicobacter pylori, but its dynamics remain incompletely understood. Here we use an in vitro transformation system combined with genome sequencing to study chromosomal integration patterns after natural transformation. A single transformation cycle results in up to 21 imports, and repeated transformations generate a...

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