OBJECTIVE The aim of this study was to test for association between MHC2TA gene polymorphisms and risk for restenosis after coronary stent placement in a group of Mexican patients. METHODS The MHC2TA-168A>G (rs3087456), 1614C>G (rs4774), and 2536G>A (rs2229320) single nucleotide polymorphisms were genotyped using 5' exonuclease TaqMan genotyping assays in a group of 202 patients, who underwen...

OBJECTIVES To develop a statistical model to assess the risk of early closure and restenosis on the basis of the information available at the time of stent implantation. DESIGN An exploratory forward, stepwise multivariate logistic regression for each adverse event and multivariate polychotomous analysis for both events. SETTING Tertiary referral centre for interventional treatment of coron...

OBJECTIVE We prospectively investigate the relation between baseline circulating endothelial progenitor cells and the subsequent development of restenosis after angioplasty of hemodialysis vascular access. BACKGROUND Effect of angioplasty for hemodialysis vascular access is greatly attenuated by early and frequent restenosis. Circulating endothelial progenitor cells (EPCs) play a key role in ...

Drug-eluting stents (DESs) prevail in the treatment of carotid artery diseases in the interventional cardiology world owing to their efficacy for significant reduction of restenosis. A current successful DES requires a polymer coating for drug delivery. Clinical trials examining several pharmaceutical agents have demonstrated marked reduction in restenosis following stenting. The development of...

Abstract Aims to evaluate prognostic significance of metabolic syndrome (MetS) in patients undergoing carotid artery revascularisation. Methods A systematic review and meta-analysis was performed compliance with PRISMA standards MetS endarterectomy or stenting. Short-term (<30 days) postoperative outcomes (all-cause mortality, stroke transient ischaemic attack (TIA), myocardial infarctio...

OBJECTIVES The purpose of this study was to use volumetric intravascular ultrasound analysis of Palmaz-Schatz stents to assess the in-stent restenotic process. BACKGROUND By reducing lesion elastic recoil and chronic arterial remodeling, stents improve the long-term results of coronary angioplasty. However, stents are prone to the development of neointimal hyperplasia. Angiographic studies of...

Patients with restenosis after coronary artery stent implantation may present with recurrent ischaemia, stable angina, and acute coronary syndromes. Restenosis may also be asymptomatic (without ischaemia), detected only on repeat angiography. Previous studies have demonstrated that angiographic measures including both in-stent and in-segment late loss and percentage diameter stenosis are valid ...

AIMS The aim of the study was to compare the 10-year follow-up results of patients with or without restenosis following single-vessel percutaneous transluminal coronary angioplasty (PTCA). METHODS AND RESULTS A total of 313 patients with successful PTCA (> or = 20% reduction in luminal diameter narrowing without acute complications) and a control angiography 6 months after PTCA were included ...

Balloon-stented angioplasty is a common treatment for carotid arterial atherosclerosis. Clinical studies have shown that within 6 months of the initial procedure, 25% of all stented-angioplasty patients develop restenosis, a postoperative narrowing of the artery due to plaque accumulation onto the stent. While hemodynamics, and more specifically low oscillatory wall-shear stress have been ident...

The repair of vascular injury is a concerted response involving complex signaling pathway that contributes to the clinical feature of post─angioplasty restenosis . Vascular injury leads to the activation of various biological cells and the release of numerous vasoactive, thrombogenic, and mitogenic factors in the process of restenosis. Restenosis is histologically attributed to neointimal hyper...