Anemia is a unique side effect in Korean gastric cancer patients after S-1 monotherapy. We studied gastric cancer patients from a phase II trial of S-1 monotherapy with a 2-week treatment and 1-week rest schedule. Patients from a phase II trial of S-1 monotherapy with a 4-week treatment and 2-week rest were used as a reference group. The patients were categorized into two groups based on the de...

Nurse Rostering is a combinatorial problem hard to solve due to its size and complexity. Several real world details that arise in practice make computerized approaches to the problem indispensable. The specifications of the problem that we solve are those defined in the Nurse Rostering Competition INRC2010. In this contribution, we solve the Nurse Rostering Problem by partitioning the original ...

Many cadets still cannot manage their sleep time properly, thus affecting study patterns and time. The schedule for extracurricular activities is quite tight, so the rest reduced. This results in decreased motivation to learn. aims analyze influence of learning methods, activities, perceptions campus environment on character Politeknik Ilmu Pelayaran (PIP). uses a quantitative approach populati...

OBJECTIVE To assess clinical efficacy of controlled-release oxycodone (CRO) 20 mg on a 12-h dosing schedule in this prospective, randomised, placebo-controlled, double-blinded study of 40 ASA physical status I-III women undergoing breast surgery for cancer. RESEARCH DESIGN AND METHODS General anaesthesia using remifentanil and propofol was performed for surgery. Both groups received premedica...

Studies in Polar Base stations, where personnel have no access to sunlight during winter, have reported circadian misalignment, free-running of the sleep-wake rhythm, and sleep problems. Here we tested light as a countermeasure to circadian misalignment in personnel of the Concordia Polar Base station during the polar winter. We hypothesized that entrainment of the circadian pacemaker to a 24-h...