In a study RBC-Plasma lithium ratios in manic patients treated with lithium we found that lithium responders had higher lithium ratios than lithium non-responders. There was, however, no cut off value which could differentiate lithium responders from non-responders.

Aim . To determine quantitative criteria for assessing the therapeutic benefits and most informative time frames after cardiac resynchronization therapy (CRT) to assess its long-term effectiveness (1, 2, 3 years of follow-up) based on retrospective analysis. CRT effectiveness, parameters left ventricular (LV) reverse remodeling signs characterizing clinical response were considered. Material me...

OBJECTIVE The aim of this study was to investigate whether genetic variants can identify patients with venous thromboembolism (VTE) at an increased risk of bleeding with warfarin. METHODS Hokusai-venous thromboembolism (Hokusai VTE), a randomised, multinational, double-blind, non-inferiority trial, evaluated the safety and efficacy of edoxaban versus warfarin in patients with VTE initially tr...

Compared with the pursed-lip breathing technique, acute application of portable noninvasive ventilation during recovery from intermittent exercise improved end-expiratory thoracoabdominal dynamic hyperinflation (DH) in 50% patients COPD (DH responders). DH responders, compared nonresponders, exhibited a reduction predominantly driven by abdominal compartment that effectively offset rib cage DH....

The prevention of hepatitis B is important, since it is responsible for significant morbidity and mortality around the world. Unfortunately, hepatitis B vaccine does not always induce protective immunity. The lack of immune response to vaccine (non-responders) can depend on individual characteristics. The objective of this study was to correlate the CD26/DPPIV cellular expression and DPPIV seru...