AIM Lower respiratory tract infections including mainly pneumonia represent an important public health problem leading to high mortality and mobidity rates in children aged below five years in developing countries including our country. Vitamin D deficiency has been associated with increased risk of rickets/osteomalacia, various cancers, autoimmune diseases, hyperproliferative skin diseases, ca...

conclusions infection with hmpv and rsv are most frequent infections among pediatric patients with respiratory tract symptoms. coinfection with these viruses may exacerbate the clinical symptoms and increase hospitalization rates, especially in children younger than one year old. results the hmpv and rsv were detected in 44 (15.7%) and 84 (30.0%) samples, respectively. coinfection with both vir...

  Background :Respiratory viruses are the leading cause of respiratory tract infections among children and are responsible for causing morbidity and mortality worldwide. This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics.   Methods : In this descriptive cross sectional study, throat swabs and wash speci...

Acute otitis media occurs mostly after upper respiratory tract infection; the causative bacteria are those colonized in the nasopharynx. We studied 709 episodes of upper respiratory tract infection and found that children with no bacteria in the nasopharynx were at low risk for acute otitis media, whereas children with 3 pathogenic bacteria were at the greatest risk.

Tracheobronchomegaly (TBM) or Mounier Kuhn syndrome is a rare disorder of uncertain aetiology characterized by marked dilatation of trachea and bronchi and recurrent lower respiratory tract infection. We report a case in a 20 year old male presenting with recurrent lower respiratory tract infection.

Respiratory syncytial virus (RSV) is a common cause of seasonal respiratory viral infection in patients who have undergone hematopoietic stem cell transplantation. RSV usually presents as an upper respiratory tract infection in this patient population but may progress rapidly to lower respiratory tract infection. Available therapies that have been used for the treatment of RSV infections are li...

In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isola...

Acute respiratory tract infection is a leading cause of significant morbidity worldwide. It is one of the most important causes of mortality in infants and young children and disabilityadjusted life years lost in developing countries (WHO 2009). Although some viruses, such as influenza virus, respiratory syncytial virus and human adenovirus are responsible for most acute respiratory tract infec...

BACKGROUND Lower respiratory tract infections are among the most common infectious diseases of humans worldwide and continue to be a major cause of morbidity in Nigeria. This study focused on determining the microbial agents of lower respiratory tract infections, the effect of age and gender on its prevalence, and the susceptibility profile of bacterial isolates. METHODS Sputum specimens were...

BACKGROUND More than 75,000 total hip replacements were performed in England and Wales in 2014, and this figure is predicted to increase. Trends in mortality and complications following total hip replacement from 2005 to 2014 were evaluated to quantify risk and to identify "at-risk" groups to better inform recommendations for patient care. METHODS Our primary analysis estimated 90-day inpatie...