Abstract Disruption of endothelial barrier is a crucial factor in the pathogenesis tissue inflammation, hallmark inflammatory diseases such as diabetes and atherosclerosis. Increased permeability occurs because loss cell–cell contacts disruption cell–extracellular matrix (ECM) adhesions. Vascular injury associated with activation coagulation cascade release thrombin, which increases by activati...

This article seeks to set out the application of right freedom expression in particular context criminal law, taking into account developments other Southern African jurisdictions where appropriate. In particular, examines contempt court, sexual morality, and pornography. Possible future applications are also identified. Ultimately affirms primary importance expression, argues that should be ze...