نتایج جستجو برای: resistant tuberculosis
تعداد نتایج: 281933 فیلتر نتایج به سال:
In Africa, incidence and prevalence of drug-resistant tuberculosis have been assumed to be low. However, investigation after a 2005 outbreak of extensively drug-resistant tuberculosis in KwaZulu-Natal Province, South Africa, found that the incidence rate for multidrug-resistant tuberculosis in KwaZulu-Natal was among the highest globally and would be higher if case-finding efforts were intensif...
In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the...
A 17-year-old female diagnosed to have multidrug-resistant pulmonary tuberculosis (MDR-TB), presented with Poncet's arthritis which responded to second-line anti-TB treatment. Poncet's disease is more commonly present in association with extra-pulmonary TB and involves large and small joints. However, our patient had pulmonary MDR-TB and small joint involvement.
Tuberculosis is a highly infectious disease. It usually infects the lung, but dissemination to different organs results in severe form of tuberculosis, i.e., disseminated tuberculosis. The situation becomes even more challenging when infection due multidrug-resistant strains Mycobacterium present case very rare one where 17-year-old Indian girl presented with headache, vomiting, cough expectora...
Affiliations: Dept of Medicine and Office of Global Health, UT Southwestern Medical Center, Dallas, TX, and College of Pharmacy and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. Epidemiology and Medical Statistics Unit, Dept of Biomedical Sciences, University of Sassari–Research, Medical Education and Professional Development Unit, AOU Sassari, Sassari, and WHO Coll...
Linezolid (LZD) has become increasingly important for the treatment of multidrug-resistant tuberculosis (MDR-TB), but its mechanisms of resistance are not well characterized. We isolated 32 mutants ofMycobacterium tuberculosiswith reduced susceptibility to LZD, which was accounted for byrrlandrplCmutations in almost equal proportions, causing lower and higher MICs, respectively. Our findings pr...
Drug-resistant Mycobacterium tuberculosis is challenging elimination of tuberculosis (TB). We evaluated risk factors for TB and levels of second-line drug resistance in M. tuberculosis in patients in Europe with multidrug-resistant (MDR) TB. A total of 380 patients with MDR TB and 376 patients with non-MDR TB were enrolled at 23 centers in 16 countries in Europe during 2010-2011. A total of 52....
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