Research using human subjects will continue to play an important role as part of a great humanitarian effort to understand ourselves better and to relieve distress and disease. To use human beings as subjects in medical experiments – or any type of research – is a special privilege which carries with it special ethical responsibilities Harold T. Shapiro President Emeritus University of Michigan...

A little more than a year ago, we published an editorial calling for papers describing research on human subjects (1). Research on human subjects is becoming more feasible because of advances in methodology, and investigations on human subjects are needed to advance the areas of human physiology and disease covered by the Journal. Patient-oriented research in particular is often perceived as be...