BACKGROUND Hand-held NB-UVB units are lightweight devices that may overcome the need to treat vitiligo in hospital-based phototherapy cabinets, allowing early treatment at home that may enhance the likelihood of successful repigmentation. The pilot Hi-Light trial examined the feasibility of conducting a large multi-centre randomised controlled trial (RCT) on the use of such devices by exploring...

Abstract Vitiligo is a common acquired disorder of depigmentation that occurs as result melanocyte loss. Surgical therapies are indicated in patients with stable disease who fail to respond medical therapies. This mostly includes autologous grafting techniques both tissue and cellular (both cultured noncultured). Common recipient site preparation include dermabrasion, suction blistering, liquid...

The aim of the present study was to establish an immunofluorescence method of antibody detection to identify melanocytes in the serum of vitiligo patients. Furthermore, we aimed to establish a method for the culture and proliferation of autologous pure melanocytes and to observe the effect of their transplantation for the treatment of vitiligo. Suspension of epidermal cells with melanocytes was...

tients showed inflammatory lesions that waned after MEL treatment (P .003), and 5 patients had hyperkeratotic lesions that subsequently disappeared (P .02). Three of 13 patients’ areas of disease showed decreased infiltration during the study. Six patients reported scalp pain before or during the study, but none by the end (P .008). While 10 of 13 patients reported itching at baseline or during...

Introduction: The authors have carried out a retrospective analysis of data from 26 patients with developing vitiligo who were treated with oral mini-pulse of dexamethasone. Clinical response and side effects were evaluated at monthly intervals. Of the 26 patients included in the study, 12 (46.2%) presented a repigmentation of lesions, 11 (42.3%) stabilized, and 3 (11.5%) experienced a worsenin...

Vitiligo is a pigmentation disorder involving 1% of the population. One of the first line depigmenting agents is monobenzyl ether of hydroquinone (MBEH). Repigmentation following sun exposure; however, can occur after successful treatment with MBEH. This study describes a 54-year-old gentleman who presented with a 7-year history of hyperpigmented lesions on his face following depigmentati...