In human systemic lupus erythematosus (SLE), diverse autoantibodies accumulate over years before disease manifestation. Unaffected relatives of SLE patients frequently share a sustained production of autoantibodies with indiscriminable specificity, usually without ever acquiring the disease. We studied relations of IgG autoantibody profiles and peripheral blood activated regulatory T-cells (aTr...

BACKGROUND Little is known about compliance with colonoscopy as a screening method in first-degree relatives of patients with large adenomas. Aims To evaluate the compliance with screening colonoscopy among this population, and its determinants. METHODS Data were obtained from the family part of the GEADE study, a study on genetic factors of colorectal adenomas. Index cases were 306 patients ...

Introduction: Impulsivity is a core characteristic of bipolar disorder and it was observed as elevated in individuals with the disorder and in their relatives. Both impulsivity and history of maltreatment are risk factors for suicide attempts, however, these two key variables may not be independent, given the fact that parental impulsivity and associated social context could increase the risk o...

Increased intestinal permeability in patients with Crohn's disease and their first degree relatives has been proposed as an aetiological factor. The nine hour overnight urinary excretion of polyethyleneglycol-400 (PEG-400) and three inert sugars (lactulose, l-rhamnose, and mannitol) was used to test the permeation in 47 patients with Crohn's disease of whom 18 had at least one first degree rela...

The present study aimed to (1) identify the difficulties most frequently reported by individuals with severe traumatic brain injury (TBI) at the time of discharge from a sub-acute rehabilitation brain injury unit as well as difficulties reported by their relatives, (2) compare patients' and relatives' reports of patient difficulties, and (3) explore the role of injury severity, disability and o...

the acupuncture is a safe medical treatment method. regarding to an absence of adverse effects, this method is considered as the best interventions in smoke cession and relieving the threatening pains. churchill mentioned that most people watched some tv movies related to using of acupuncture in anesthetizing the surgical patients some people experienced acupuncture by themselves or relatives. ...

background: there are many risk factors besides age and immune suppression for herpes zoster. family history as a risk factor is suggested in some recent studies. the aim of this study was to evaluate the association between herpes zoster and family history. methods: this case-control study was undertaken in farshchian hospital, hamadan, iran. “case group” included patients with confirmed diagn...

the diabetes is an autoimmune disease, in which the role of autoantibodies is of a specific importance. the appearance of these autoantibodies can be the first symptom in the serum of type i diabetic patients, which may appear ten years before onset of the disease. the most important autoantibodies include glutamic acid decarboxylase autoantibodies (gad65-ab). this can be used as a good tool fo...

background the altered levels of some essential trace elements and antioxidant minerals have been observed in diabetic patients. objectives the aim of the present study was to compare the concentrations of essential trace elements, copper (cu), zinc (zn), and iron (fe) in the serum of patients who have type 2 diabetes mellitus (t2dm) with those of their non-diabetic first-degree relatives (fdr)...

background changes in vital signs may affect the myocardial oxygen demand. massage therapy has been used in intensive care units to relive patients’ physical and psychological problems. in all of the studies massaging has been done by a nurse and the patients’ family did not have any role. objectives the present study aimed to examine the effects of massage therapy by patient’s relative on vita...