Craving, defined as the subjective experience of an urge or desire to use substances, has been identified in clinical, laboratory, and preclinical studies as a significant predictor of substance use, substance use disorder, and relapse following treatment for a substance use disorder. Various models of craving have been proposed from biological, cognitive, and/or affective perspectives, and, co...

A recall has been issued by Ortho-McNeil-Janssen Pharmaceuticals for specific lots of 3-mg Risperdal (risperidone) tablets and 2-mg generic risperidone tablets because of an uncharacteristic musty odor thought to come from trace amounts of 2,4,6-tribromoanisole (TBA), the metabolite of a chemical fungicide used to treat wooden pallets on which the products are stored.1 McNeil Consumer Health ha...

BACKGROUND Major depressive disorder is a common debilitating illness that is the second leading contributor to the global burden of disease. Unfortunately, about 30 % of patients do not respond to adequate trials of antidepressants and/or psychotherapies. About 45-60 % of such treatment-resistant patients will remit with electroconvulsive therapy (ECT). However, relapse rates are high followin...

www.thelancet.com Vol 380 September 22, 2012 1055 trial requires it to be viewed in the context of the totality of evidence; the estimates of eff ect seen in IST-3 were comparable with, and reinforced the results of, previous trials. Fatovich and colleagues state that we had decided “ordinal analysis was not appropriate”; this was the view of the steering committee in 2009. However, as stated i...

Recent shifts to briefer hospitalization and an emphasis on community care have emphasized the significance of patient-family interactions in this phase of treatment. Psychoeducational family programs designed to increase medication compliance and effectiveness in coping with stressors have been successful in reducing the risk of relapse in the first year following hospital discharge. Various m...

BACKGROUND Pharmacological interventions alone do not provide sufficient benefit for some individuals with bipolar disorder. AIMS To determine the effectiveness of psychosocial interventions for the prevention of relapse in bipolar disorder. METHOD A systematic review and meta-analysis of randomised or quasi-randomised controlled trials were conducted. RESULTS Cognitive-behavioural therap...

Gognitive-behavioral approaches to alcohol and drug use disorders have received considerable empirical support over the past 20 years. One cognitive-behavioral treatment, relapse prevention, was initially designed as an adjunct to existing treatments. It has also been extensively used as a stand-alone treatment and serves as the basis for several other cognitive and behavioral treatments. After...

purpose: to ascertain the role of social support and positive affect in prediction of addiction relapse. materials and methods: the research method was a causal-comparison. population included all the clients seeking for medical advice in the centers for addiction treatment in saravan and iranshar. the sample includes 186 participants (83 participants had no relapse and 83 participants had rela...