A water soluble, Bronsted acid, 5-sulfosalicylic acid as an efficient organocatalyst was used for the synthesis of physiologically active 2-substituted benzimidazole derivatives from o-phenylenediamine and aromatic aldehydes in ethanol at reflux condition. Cost-effectiveness, use of non-hazardous solvents, metal free and commercially available catalyst, single-step, environmentally fri...

introduction: gastroesophageal reflux (ger) is the most common of esophageal disorder in all ages.  ger defined as passage of gastric contents into the esophagus, and ger disease (gerd), (symptoms or complications of ger), are common pediatric problems. clinical manifestations of gerd in infants include regurgitation, irritability, choking, gagging vomiting, poor weight gain and respiratory dis...

Aim: Urinary reflux is a probable reason of nephrolithiasis among children. This study aimed to assess the relationship between urinary reflux and other reason of stone formation in children.Methods: This cross-sectional study was carried out with 199 children diagnosed with nephrolithiasis using ultrasonography. They were hospitalized in a referral children hospital in an urban area of in Iran...

Shortcut Methods for Complex Distillation Columns: Part 1 -Minimum Reflux This two-part paper presents in detail the theory for calculating via shortcut methods the minimum reflux conditions and the number of stages and feed tray location for ordinary and thermally coupled columns. Nonadjacent key components are permitted. In this paper, part 1, the approximations made to estimate minimum reflu...

A total of 98 patients, who had undergone gastric surgery (23), or who had peptic ulcers (56), or who had normal endoscopic findings (19) underwent gastric biopsy, together with measurement of pH and total bile acid concentration, in their fasting gastric juice. The biopsy specimens were stained by the Warthin-Starry method for Campylobacter like organisms and were also graded "blind," as descr...

OBJECTIVES Gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) are very common and controversial diseases. The authors have previously reviewed clinical practice guidelines (CPGs) on reflux disease, and these major consensus statements differ on what constitutes ideal management. The aim is to critically review existing protocols for reflux based on CPG recommendations and...

Co3O4/NiO@GQDs@SO3H nanocatalyst has been used as an effective catalyst for the preparation of benzopyranopyridines through a four-component reaction of salicylaldehydes, thiols and 2 equiv of malononitrile under reflux condition in ethanol. The catalyst has been characterized by FT-IR, XRD, SEM, EDS, BET, XPS, TGA and VSM. Atom economy, reusable catalyst, low catalyst loading, applicability to...