Background: The expected ageing of the population and increase in number patients with osteoporosis require a correct approach to identification individuals high fracture risk, their rational routing for work-up timely prescription therapy. A preliminary analysis characteristics referred specialized centers may help optimize medical care these patients.
 Aim: To analyze profile densitometr...

The objective : to establish the reasons of discrepancy between preliminary and final clinical diagnoses in patients admitted TB inpatient unit, determine ways improve diagnosis tuberculosis at pre-hospital stage. Subjects Methods . We studied 130 medical records (77 HIV negative - Group 1, 53 positive – 2) unit hospital 2014-2022, whom (TB) was excluded after examination. Results In all were d...

OBJECTIVES To investigate the clinical characteristics of patients with trigeminal neuralgia referred to surgery in a center of reference. METHODS We evaluated the general characteristics of 395 patients with trigeminal neuralgia referred to neurosurgery as treatment. They corresponded to 2 samples of 1984 and 2004. The EDOF-HC protocol (Orofacial Pain Questionnaire) and the medical profile w...

IMPORTANCE Clinical whole-exome sequencing is increasingly used for diagnostic evaluation of patients with suspected genetic disorders. OBJECTIVE To perform clinical whole-exome sequencing and report (1) the rate of molecular diagnosis among phenotypic groups, (2) the spectrum of genetic alterations contributing to disease, and (3) the prevalence of medically actionable incidental findings su...

BACKGROUND Alzheimer's disease (AD) is the most common cause of dementia and early and accurate diagnosis is important. Olfactory dysfunction is an early sign of AD. The contribution by test of olfactory function has been surveyed in AD vs a line of conditions but remains to be settled in the workup of unselected patients referred with suspected dementia. METHODS We performed a two-step inves...