INTRODUCTION Female sexual desire and arousal problems have been shown to have a heritable component of moderate size. Previous molecular genetic studies on sexual desire have mainly focused on genes associated with neurotransmitters such as dopamine and serotonin. Nevertheless, there is reason to believe that hormones with more specific functions concerning sexuality could have an impact on se...

This article presents data from a validation sample of 390 premenopausal women clinically diagnosed with hypoactive sexual desire disorder (HSDD) enrolled in the HSDD Registry for Women. Participants completed validated measures of sexual distress (e.g., Female Sexual Distress Scale Revised, Question 13) and sexual function including desire (e.g., Female Sexual Function Index). Results showed t...

The present study examined effects of testosterone on hypoactive sexual desire in pre- and postmenopausal women (treated) compared with an age-matched reference group (reference). Treated participants received 100 mg of testosterone cypionate in oil injected intramuscularly (i.m.) monthly for 3 months. We measured salivary testosterone and scores on the Sexual Desire Inventory pretreatment and ...

conclusions according to the obtained results, females in the rural areas had lower sexual function than the ones in the urban areas. it is suggested to establish female sexual health units in healthcare centers to give female sexual function consultation adjusted with awareness and culture of females and consider the existing problems. background healthy sexual function can be considered as an...

BACKGROUND In the professional literature and among our professional societies, female sexual dysfunction nomenclature and diagnostic criterion sets have been the source of considerable controversy. Recently, a consensus group, supported by the International Society for Women's Sexual Health, published its recommendations for nosology and nomenclature, which included only one type of arousal dy...

The sexual system evolved to motivate reproductive acts. As such, its manifestations (e.g., sexual desire and behavior) are not necessarily related to emotional attachments. Still, within romantic relationships, sexual desire can motivate the attachment bonding process and lead to intensely meaningful experiences that affect the quality of a relationship and its fate. In this article, we review...

BACKGROUND Oophorectomy reduces serum testosterone levels. We studied the efficacy and safety of transdermal testosterone in treating hypoactive sexual desire disorder in surgically menopausal women. METHODS A 24-week, randomized, double-blind, placebo-controlled, parallel-group, multicenter trial was conducted in women (aged 24-70 years) who developed distressful low sexual desire after bila...