background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

Background: Abdominal pregnancy is a rare ectopic in which the baby grows up peritoneal cavity exclusive of tubal, ovarian, or intraligamentary implantations. has very high maternal and fetal morbidity mortality. Therefore, early recognition prompt management remain challenges for treating physician. A thorough examination newborn critical to rule out congenital anomalies. We reported 24-year-o...

there is a continuing need to identify new agents that are active in ovarian cancer. etoposide is a derivative of the plant alkaloid epipodophyllotoxin. the availability of etoposide in oral preparation allows prolonged administration by the oral route. in this study, activity and toxicity of etoposide in women with recurrent ovarian cancer are described from a case series of women with recurre...

INTRODUCTION Several different foods have been implicated in inducing the delayed and very significant vomiting and sometimes diarrhea that occurs in food protein-induced enterocolitis syndrome. While immunoglobulin E is not involved, the mechanism(s) that result in the food-induced gastrointestinal symptoms are unclear, although T cell activation has been considered. We report four cases of fo...

Recurrent meningitis in children, although rare, results in an increased risk of acute complications and long-term morbidity. We did a retrospective case series to analyze the clinical presentation, predisposing factors, treatment and outcome of children with recurrent meningitis admitted at Shifa International hospital, Islamabad. All children presenting with recurrent meningitis from December...

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome has various presentations. We report on a case of MELAS in which alternate-sided homonymous hemianopia was the main symptom of recurrent neurological defects. A 19-year-old woman suffered from blurred vision, headaches, vomiting, and fever that subsided within days. The ophthalmic examination demonstrate...

It is generally accepted that the risk for fetal infection is greatest with maternal primary cytomegalovirus CMV infection and much less likely with recurrent infection. Here, we report a fatal case of congenital CMV infection following recurrent maternal infection after a 7-year interval. A 3-month-old female baby presented with fever, jaundice, vomiting and stopping breast-feeding. Physical e...

this study was designed to assess the role of first-line chemotherapy with 5-fu and platinum in the treatment of advanced or recurrent cervical cancer, ten patients with advanced or recurrent cancer of the cervix, with no prior chemotherapy were entered in phase ii trial, from oct. 2000 to nov. 2001. eight patients were treated with cis-platinum (50 mg/m2 over 60 minutes in first day) followed ...