نتایج جستجو برای: razy 251
تعداد نتایج: 6748 فیلتر نتایج به سال:
251-labelled human trypsin metabolism has been investigated in man. Three subjects received 1251-trypsin and 1311-albumin intravenously. Against a background secretin infusion (lu/kg/h), trypsin decayed biexponentially from the serum with half-lives of 17.5, 21, and 24 minutes for the rapid disappearance phase and 520, 540, and 560 minutes for the slow phase. Between 130% and 38% of the 1251 in...
We have used ‘251-laheled vasoactive intestinal peptide (VIP) to study the kinetics, stoichiometry, and chemical specificity with which the labeled peptide binds to dispersed acinar cells prepared from guinea pig pancreas. Binding of ‘2”I-VIP to pancreatic acinar cells was moderately rapid, reversible, specific, saturable, and depended on incubation temperature. Deterioration of ‘2sI-VIP incuba...
BACKGROUND Increased levels of interleukin-8 (IL-8) and interleukin-6 (IL-6) in acute human brucellosis have been reported. Previous studies have shown that the production and level of IL-6 and IL-8 cytokines are associated with the polymorphism of the encoding genes. OBJECTIVE To investigate the probable association between IL-6 (-174 C/G) and IL-8 (-251 A/T) gene polymorphisms and susceptib...
Although it is well established that cyclin-dependent kinases phosphorylate and inactivate Rb, the Raf-1 kinase physically interacts with Rb and initiates the phosphorylation cascade early in the cell cycle. We have identified an orally active small molecule, Rb/Raf-1 disruptor 251 (RRD-251), that potently and selectively disrupts the Rb/Raf-1 but not Rb/E2F, Rb/prohibitin, Rb/cyclin E, and Rb/...
Mariologia nie jest tematem centralnym Homilii Paschalnej Melitona z Sardes, ale pojawia się zawsze w kontekście rozważań na temat zbawczej roli Chrystusa. Maryja tekście cztery razy, r. 66, 70, 71 i 104, czego trzy razy pierwszej jej części dotyczącej typologicznej interpretacji Wj 12 (r. 70 71) jeden raz Epilogu (r.104). W Meliton przedstawia tajemnicę wcielenia słowami „On to Dziewicy wziął ...
BACKGROUND Exportin 1 (XPO1), also called chromosome region maintenance 1 (CRM1), is the sole exportin mediating transport of many multiple tumor suppressor proteins out of the nucleus. AIM AND METHODS To verify the hypothesis that XPO1 inhibition affects prostate cancer (PCa) metastatic potential, orally available, potent and selective, SINE compounds, Selinexor (KPT- 330) and KPT-251, were ...
The DNA duplex corresponding to the entire length (126 nucleotides) of the precursor for an Escherichia coli tyrosine tRNA has been synthesized. Duplex [I] (Sekiya, T., Besmer, P., Takeya, T., and Khorana, H. G.(1976) J. Biol. Chem. 251, 634-641), corresponding to the nucleotide sequence 1-26, containing single-stranded ends and carrying one appropriately labeled 5'-phosphate group, was joined ...
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