This article proposes a comprehensive investigation of the automatic classification of functional gait disorders based solely on ground reaction force (GRF) measurements. The aim of the study is twofold: (1) to investigate the suitability of stateof-the-art GRF parameterization techniques (representations) for the discrimination of functional gait disorders; and (2) to provide a first performan...

BACKGROUND Partial body weight support (BWS) systems have been broadly used with treadmills as a strategy for gait training of individuals with gait impairments. Considering that we usually walk on level ground and that BWS is achieved by altering the load on the plantar surface of the foot, it would be important to investigate some ground reaction force (GRF) parameters in healthy individuals ...

The literature contains some hypotheses regarding the most favorable ground reaction force (GRF) for sprint running and how it might be achieved. This study tested the relevance of these hypotheses to the acceleration phase of a sprint, using GRF impulse as the GRF variable of interest. Thirty-six athletes performed maximal-effort sprints from which video and GRF data were collected at the 16-m...

To test the hypothesis that orexin-B acts directly on the anterior pituitary to regulate LH and growth hormone (GH) secretion, anterior pituitary cells from prepuberal gilts were studied in primary culture. On day 4 of culture, 10(5) cells/well were challenged with 0.1, 10 or 1000 nM GnRH; 10, 100 or 1000 nM [Ala15]-hGRF-(1-29)NH2 or 0.1, 1, 10 or 100 nM, orexin-B individually or in combination...

BACKGROUND Changes in performance of standing up from a chair have been related to measures of strength or power. However, the sit-to-stand (STS) transfer requires that the individual exerts forces with appropriate magnitude and timing. These coordinative aspects have received less attention. This study aims to analyze differences in STS performance in older people based on measures that are de...

BACKGROUND Chronic obstructive pulmonary disease (COPD) is a respiratory disorder with increasing prevalence and mortality. It is associated with airway obstruction, increased airway hyper-responsiveness (AHR), and ongoing airway and lung inflammation dominated by CD8 lymphocytes and neutrophils. Single-nucleotide polymorphisms (SNPs) in a disintegrin and metalloprotease 33 (ADAM33) gene have b...

We have examined the regulation of GH secretion from monolayer cultures of prepubertal male lamb anterior pituitary cells. Growth hormone-releasing factor (GRF 1-44) stimulated GH release in a dose-related manner : the maximal effective dose was 10IO M, which caused a 500 % increase in basal GH secretion, while the half-maximal effect was reached with a dose of 2.5 x 10-&dquo;M (ED 5Q ). Thyrot...

To determine whether long-term administration of growth hormone (GH)-releasing factor (GRF) and(or) thyrotropin-releasing hormone (TRH) alters ovarian follicular fluid (FFL) concentrations of insulin-like growth factor-I (IGF-I), progesterone, and estradiol (E2), and follicular growth, Friesian x Hereford heifers (n = 47; 346 +/- 3 kg) were divided into the following four groups: control (vehic...

BACKGROUND Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch continuously over prolonged periods of time. Kettlebell sport and weightlifting involve similar exercises, however, their traditional u...

We introduce an algorithm for a search of extremal fractal curves in large curve classes. It heavily uses SAT-solvers—heuristic algorithms that find models CNF boolean formulas. Our was implemented and applied to the surjective $$\gamma :[0,1]\rightarrow [0,1]^d$$ with minimal dilation $$\begin{aligned} \sup _{t_1<t_2}\frac{\Vert \gamma (t_2)-\gamma (t_1)\Vert ^d}{t_2-t_1}. \end{aligned}$$ repo...