Tianxiao Huan, Qingying Meng, Mohamed A. Saleh, Allison E. Norlander, Roby Joehanes, Jun Zhu, Brian H. Chen, Bin Zhang, Andrew D. Johnson, Saixia Ying, Paul Courchesne, Nalini Raghavachari, Richard Wang, Poching Liu, The International Consortium for Blood Pressure GWAS (ICBP), Christopher J. O'Donnell, Ramachandran Vasan, Peter J. Munson, Meena S. Madhur, David G. Harrison, Xia Yang, and Daniel...

Approved: ___________________________________ Thesis Supervisor ____________________________________ Title and Department ____________________________________ Date 1 REGULATION OF GENE EXPRESSION IN CYSTIC FIBROSIS: IMPLICATIONS FOR BIOLOGY AND THERAPEUTICS by Shyam Ramachandran A thesis submitted in partial fulfillment of the requirements for the Doctor of Philosophy degree in Genetics in the ...

This article supplements our earlier paper on synaesthesia published in JCS (Ramachandran & Hubbard, 2001a). We discuss the phenomenology of synaesthesia in greater detail, raise several new questions that have emerged from recent studies, and suggest some tentative answers to these questions. I: Robustness of Synaesthetic Effects It was Francis Galton (1880) who first reported the condition ca...

Distributed Shared Memory (DSM) offers a convenient support for distributed applications. It can be viewed as an alternative to the message passing programming model. DSM has been developed through research projects mostly: Ivy [Li 86], Clouds [Ramachandran 88], Munin [Carter 91], Mirage [Fleisch 89] for example. Meanwhile, efforts towards industrial products have been made : Treadmarks [Kelehe...

background: meict is the first chlorotoxin-like peptide isolated from the iranian scorpion mesobuthus eupeus. chlorotoxin (ctx) is a neurotoxin that specially binds to (mmp-2) on ma-lignant cells and now is used in treatment of glioma. in the present study, we have used homology modeling to propose the 3d structure of meictand analyze its interaction with mmp-2 and its snp types. methods:the st...

that the ‘‘forbidden [bridge] region is well-populated in folded proteins, which can provide longer-range intramolecular hydrogen-bond partners.’’ However, using only a hard sphere model, Ramachandran and colleagues predicted the f and c combinations as a function of s that are observed in proteins of known structure. In particular, they showed that f and c combinations in the bridge region are...

We study the thermodynamic behavior of a model protein with 54 amino acids that forms a three-helix bundle in its native state. The model contains three types of amino acids and five to six atoms per amino acid and has the Ramachandran torsional angles phi(i), psi(i) as its degrees of freedom. The force field is based on hydrogen bonds and effective hydrophobicity forces. For a suitable choice ...

RAMACHANDRAN, RAMYA. Investigation of Surface States in Gallium Nitride Devices using a New High Frequency Measurement Technique. (Under the direction of Dr. Douglas W. Barlage). Surface states place a limitation on the high-frequency behavior of Gallium Nitride devices by causing RF dispersion. They are also a source of undesirable 1/f noise. This thesis specifically aims to explore techniques...

Editor’s note: Few scientists contribute an idea of such clarity and power that it appears in all the discipline’s textbooks and bears the author’s name. For the contribution to be relevant and universally employed almost forty years after it first appeared is even less common. Structural biology lost the author of such an idea with the death of G.N. Ramachandran, whose picture appears on the c...

2:30 p.m. 2:45 p.m. OF MICE, MEN AND PIGS: LOSS OF CFTR PRODUCES ABNORMAL TRACHEAL DEVELOPMENT D.K. Meyerholz, S. Ramachandran, D.A. Stoltz, M.J. Welsh, and P.B. McCray, Jr. Departments of Pathology, Pediatrics, Internal Medicine, Molecular Physiology and Biophysics, and Howard Hughes Medical Institute, Roy Carver College of Medicine, University of Iowa, Iowa City, IA Keyword: Respiratory Syste...