The issue of relative adrenocortical insufficiency (RAI) in septic shock is confused and uncertain. Multiple definitions of RAI have been proposed, but it is most commonly defined as an increment of less than 250 nmol/L in total serum cortisol level after administration of 250 microg corticotropin. RAI is associated with an increased risk of death, after adjustment for other factors that might ...

In this paper, we present evidence that alleles of several polymorphisms in the chromosomal region 19q13.2-3, encompassing the genes RAI and XPD, are associated with occurrence of basal cell carcinoma in Caucasian Americans. The association of one of these, RAI-intron1, is sufficiently strong to make mass significance unlikely (P = 0.004, chi(2)). We interpret our combined data to indicate that...

Title of Document: INTERANNUAL VARIABILITY OF SEA SURFACE TEMPERATURE IN THE EASTERN TROPICAL PACIFIC OCEAN AND CENTRAL AMERICAN RAINFALL Kristopher B. Karnauskas, Ph.D., 2007 Directed By: Professor Antonio J. Busalacchi Department of Atmospheric and Oceanic Science Sea surface temperature (SST) in the east Pacific warm pool (EPWP) plays a potentially important role in Central American rainfall...

This study was undertaken to evaluate the incidence and risk factors associated with relative adrenal insufficiency (RAI) in Korean critically-ill patients. All patients who were admitted to the Medical Intensive Care Unit (MICU) of Samsung Medical Center between January 1, 2006 and April 30, 2007 were prospectively evaluated using a short corticotropin stimulation test on the day of admission....

Differentiated thyroid cancer (DTC) is the most common endocrine malignancy and the fifth most common cancer in women. DTC therapy requires a multimodal approach, including surgery, which is beyond the scope of this paper. However, for over 50 years, the post-operative management of the DTC post-thyroidectomy patient has included radioactive iodine (RAI) ablation and/or therapy. Before 2000, a ...

STUDY OBJECTIVES To determine the diagnostic utility of a nasal cannula/pressure transducer (NC), in comparison to thermistor (TH), during routine, clinical nocturnal polysomnography (NPSG). DESIGN We analyzed the respiratory arousal index (RAI) using TH (RAI-TH) or NC (RAI-NC) in patients with suspected sleep-disordered breathing (SDB). SETTING Sleep disorders center of a university-affili...

PURPOSE The aim of this study was to evaluate the morphological changes of rat lacrimal glands at the third month following radioiodine (RAI) treatment and the radioprotective effect of montelukast (ML) sodium against RAI-related lacrimal gland damage. METHODS Fifty female Wistar Albino rats were divided into three groups. The control group (n=10) consisted of rats with no intervention. RAI g...

We propose a constraint-based algorithm for Bayesian network structure learning called recursive autonomy identification (RAI). The RAI algorithm learns the structure by recursive application of conditional independence (CI) tests of increasing orders, edge direction and structure decomposition into autonomous substructures. In comparison to other constraintbased algorithms d-separating structu...

Because high levels of cortisol are frequently observed in patients with septic shock, low levels of serum cortisol are considered indicative of relative adrenal insufficiency (RAI). This study was performed to investigate whether pretest clinical characteristics, including basal serum cortisol levels, are predictive of serum cortisol response to corticotropin and whether basal cortisol levels ...