Cancer is one of the major causes of death all over the globe and radiotherapy is considered one of its most effective treatment methods. Designing a radiotherapy treatment plan was done entirely manually in the past. RecentlyIntensity Modulated Radiation Therapy (IMRT) was introduced as a new technology with advanced medical equipmentin the recent years. IMRT provides the opportunity to delive...

Introduction: Individual oral stent is a mouth-opening device that used in head and neck cancer radiotherapy with the intention of decreasing radiation dose to health tissues. The aim of this study was to check the dose delivered to both the hard palate and tongue when patient uses the stent during radiotherapy of tongue carcinoma. Methods and materials<stron...

Introduction: External radiotherapy is the most common method of radiotherapy which the most important problem associated with is that there is no difference between healthy and tumor tissues in dose absorption. One way to differentiate the dose sensitivity is to use metal-based nanoparticles. Bismuth oxide nanoparticles are good candidates for cancer radiotherapy. In this study, we investigate...

Introduction: Radiotherapy is an effective modality to treat esophageal carcinoma. Due to various inhomogenous tissues with a variety of physical and radiological properties which can cause uncertainty in accurate dose calculations in radiation therapy, accuracy of TPS is very important. The aim of this study was to quantify dose calculation accuracy of CoreplanTM TPS in an inh...

Background: Accurate small radiation field dosimetry is essential in modern radiotherapy techniques such as stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). Precise measurement of dosimetric parameters such as beam profile, percentage depth doses and output factor of these beams are complicated due to the electron disequilibrium and the steep dose gradients. In the p...

Background In radiotherapy, especially when treating children, minimising exposure of healthy tissue can prevent the development adverse outcomes, including second cancers. this study we propose a validated Monte Carlo framework to evaluate complete patient during paediatric brain cancer treatment. Materials and methods Organ doses were calculated for treatment diffuse midline glioma (50.4 Gy w...

Introduction Accurate estimation of the skin-absorbed dose in external radiation therapy is essential to estimating the probability of secondary carcinogenesis induction Materials and Methods Electron contamination in prostate radiotherapy was investigated using the Monte Carlo (MC) code calculation. In addition, field size dependence of the skin dose was assessed. Excess cancer risk induced by...

BACKGROUND The aim of this study was to report outcomes and late toxicity following hypofractionated accelerated radiotherapy for T2 glottic cancers. We highlight the importance of hypofractionated treatments with shorter overall treatment times, in improving outcomes for T2 glottic cancers. We also compare the biologically effective dose of hypofractionated regimes, with conventional fractiona...