understanding the mechanism of tumor resistance is critical for cancer therapy. in this study, we investigated the effect of carcinoembryonic antigen (cea) overexpression on uv-and 5-fluorouracil (5-fu)-induced apoptosis and autophagy in colorectal cancer cells. we used histone deacetylase (hdac) inhibitor, nab and dna demethylating agent, 5- azacytidine (5-aza) to induce cea expression in ht29...

g l o b a l c o m p e t i t i v e n e s s h a s r e c e n t l y b e c o m e a b i g c h a l l e n g e f o r m a n y c o m p a n i e s a r o u n d t h e w o r l d, w h i c h a r e f o r c e d t o s e e k l o w e r c o s t s a n d h i g h e r q u a l i t y f o r w h a t t h e y p r o d u c e. t h e p r o s p e r i t y o f m a n u f a c t u r i n g f i r m s d e p e n d s o n s e l e c t i n g a n...

the main objective of this study is to investigate the production factors productivity in large manufacturing sub-sectors. for this purpose, using statistical data for period 1972-2004, we have tried to study and analyze the trend and level of production factors productivity (partial and total productivity) in each sub-sectors classified according to isic two digits code. the average and margin...

to design the equipment and facilities for preservation, storage and processing of pomegranate, it is necessary to know the specific heat and thermal conductivity of the fruit components. the specific heat of exocarp, mesocarp and of seeds of pomegranate were assessed at three moisture content levels (30, 50 and 76% for seed and mesocarp; 15, 35 and 52% for exocarp) and at four temperature leve...

skin aging is a continuous process that exhibits fine and deep wrinkles, thin and transparent skin, loss of underlying fat, dry skin and itch, following decreased collagen and elastin  synthesis. both extrinsic and intrinsic agents are considered in the pathogenesis on skin aging. extrinsic factors such as sun exposure, windy and dry weather, nutrition, and lifestyle may induce premature aging,...

objective: this study aimed to determine prevalence and predisposing factors of psychiatric disorders among infertile in comparison to fertile women. materials and methods:  by a descriptive- analytic study in vali-e-asr reproductive health research center, 300 women entered the research.   symptom checklist -90 -revised (scl-90-r) test and structured researcher questionnaires were applied for ...

to compensate for some inferior properties of recycled papers, application of processing chemical aids such as chitosan can be quite effective in the wet end section of papermaking. in this study, the performance of chitosan biopolymer, individually or associated with nanobentonite was investigated as wet end additive on recycling process of white cuttings. for this purpose, the performance of ...

this qualitative study was conducted to identify the factors and barriers of entrepreneurship development from the perspective of iranian entrepreneurs. in terms of purpose, this study is applied- developmental and it is performed via descriptive phenomenological method. qualitative content analysis was used to collect the data. the study population comprised of recorded interviews with the ent...

conclusions the identified expression profiles of some examined mirnas might offer important points to consider for the treatment of naive patients and the management of chronically infected hcv patients in egypt and around the world. results our results revealed differential expression levels of the analyzed mirnas compared to the normal controls. twenty-seven mirnas (including mir-105, mir-14...

a competitive spectrophotometric method has been used for the study of complexation between cu2+, zn2+ and cd2+ (m) and 18-crown-6(18c6, b) in methanol using 4-(2-thiazolylazo) resorcinol (tar, hl) as the colorimetric complexant. absorption spectra of the species in the m-tar-18 c6 system at a various concentrations of 18c6 showed no formation of ternary complex, mlb, and the stoichiometry of t...