نتایج جستجو برای: quinoline 3 carbonitile

تعداد نتایج: 1813550  

2010
Seik Weng Ng

The K atom in the title complex, [K(C(10)H(6)NO(2))(C(10)H(7)NO(2))(3)], lies on a twofold rotation axis that relates one N,O-chelating quinoline-2-carb-oxy-lic acid to the other; their N and O atoms are cis to each other in the distorted octa-hedral coordination geometry. The K atom is also coordinated by another monodentate quinoline-2-carb-oxy-lic acid; the acid is disordered with respect to...

2011
S. Sarveswari V. Vijayakumar Seik Weng Ng Edward R. T. Tiekink

Two independent mol-ecules comprise the asymmetric unit of the title chalcone, C(25)H(17)Cl(2)NO, and while each has an E configuration about the ethyl-ene double bond, they differ in the relative orientations of the carbonyl and ethyl-ene double bonds within the prop-2-en-1-one residues, i.e. anti and syn. For each mol-ecule, the benzene [dihedral angles = 71.04 (9) and 73.34 (12)°] and prop-2...

2015
DEEPIKA JHANWAR JAIMALA SHARMA

The quinoline ring plays an important role in many biological systems. Their chemical Synthesis is flexible, can be easily adapted to prepare new derivatives and rationally devised structures, and hopefully can be a source of useful drugs in future. Anticancer activities have been studied for many quinoline derivatives. It has been known that quinoline derivatives may act as anticancer agents t...

Journal: :Cancer research 1976
K Hirao Y Shinohara H Tsuda S Fukushima M Takahashi

The effects of prolonged p.o. administration of quinoline or 2-chloroquinoline on rat liver were examined histologically. Hepatocellular carcinomas and hemangioendotheliomas were observed in the livers of rats fed a basal diet containing 0.05, 0.10, or 0.25% quinoline for about 16 to 40 weeks. However, no neoplastic changes were seen in the livers of rats fed a basal diet containing 0.05, 0.10,...

Journal: :Molecules 2017
Krzysztof Marciniec Bartosz Pawełczak Małgorzata Latocha Leszek Skrzypek Małgorzata Maciążek-Jurczyk Stanisław Boryczka

In this study, a series of regioisomeric acetylenic sulfamoylquinolines are designed, synthesized, and tested in vitro for their antiproliferative activity against three human breast cacer cell lines (T47D, MCF-7, and MDA-MB-231) and a human normal fibroblast (HFF-1) by 4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate (WST-1) assay. The antiproliferative activity o...

Journal: :journal of sciences islamic republic of iran 0

reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). reaction of diazomethane with compound 3 yielded the ester 4. compound 5 was prepared from the reaction of n, n'-dialkylethyl (or propyl) arnine with 4. addition of hydrazine hydrate to compound 4a gave 2- (2- pyridyl) quinoline-4-carboxylic acid hydrazide (6). reaction of ...

Journal: :Applied and environmental microbiology 1990
J Aislabie A K Bej H Hurst S Rothenburger R M Atlas

Several bacterial cultures were isolated that are able to degrade quinoline and to transform or to degrade methylquinolines. The degradation of quinoline by strains of Pseudomonas aeruginosa QP and P. putida QP produced hydroxyquinolines, a transient pink compound, and other undetermined products. The quinoline-degrading strains of P. aeruginosa QP and P. putida QP hydroxylated a limited number...

2011
Jun Wu Lu-Sheng Chen Qi-Kui Liu Dian-Shun Guo

The title compound, C(11)H(9)F(3)NO(+)·ClO(4) (-)·C(11)H(8)F(3)NO or [(C(11)H(8)F(3)NO)H(C(11)H(8)F(3)NO)]ClO(4), contains two 8-(2,2,2-trifluoro-eth--oxy)quinoline molecules, one of which combines a proton from perchloric acid to form the corresponding quinolinium cation. The quinolinium and quinoline rings form a cationic unit via an inter-molecular N-H⋯N hydrogen bond. The heterocyclic units...

2011
H. C. Devarajegowda H. K. Arunkashi Suresh Babu Vepuri N. Chidananda V. D. Jagadeesh Prasad

In the title compound, C(13)H(9)ClF(3)N, the quinoline ring system makes a dihedral angle of 88.8 (2)° with the cyclo-propyl ring.

Journal: :Colloids and Surfaces A: Physicochemical and Engineering Aspects 2021

Understanding the adsorption behavior of nitrogen heterocyclic compounds (NHCs) on soil minerals underlies more effective design wastewater treatment and soil/groundwater remediation. We investigated quinoline, a representative NHC, quartz sand (using Berea sandstone as model), at 3 < pH 9, in low (0.05 M) high (0.7 ionic strength solutions where NaCl was background electrolyte. Minor clay (kao...

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