Introduction: One of the current applications is the depiction of pancreatic cancer. Though DWI can be applied here, the full delineation of the tumor remains challenging. Q-space imaging, an alternative diffusion measurement, is currently applied using large diffusion weightings to access non-Gaussian diffusion in the high b-value regime and has so far only been implemented for CNS application...

•The specificity of a glutaminase subunit for synthase has been inverted•The switch was achieved by both computational and data-driven approach•The designed complexes were stable catalytically active The formation specific protein in cell is non-trivial problem given the co-existence thousands different polypeptide chains. A particularly difficult case are two glutamine amidotransferase (anthra...

A key to effective teaching is an awareness and accurate understanding of the thinking and implicit assumptions that students bring to the subject to be learned. In the absence of extensive Socratic interactions with students, one strategy to assess student thinking involves the use of concept inventories (CIs). CIs are typically multiple-choice assessments, constructed based on research into s...

This article studies the spatial dimension of social selection local elected officials that takes shape through geographical selectivity officials’ places residence. Based on data residence in Zurich and Lausanne (1980-2016), we show residential dispersion is not random but driven by a logic class socio-spatial selectivity. We also this varies according to partisan affiliation existence or elec...

We present the implementation of Distributed Constructionism (DC) through a Participatory Design (PD) methodology for an Online Learning community. The students collaborate on the content and functionality development of an online Modern Greek language course, peer review and publish content contributions, and participate in participatory design teams. Participatory design was implemented as a ...