The purpose of this study was to obtain an amorphous system with minimum unit operations that will prevent recrystallization of amorphous drugs since preparation, during processing (compression) and further storage. Amorphous celecoxib, solid dispersion (SD) of celecoxib with polyvinyl pyrrollidone (PVP) and co-precipitate with PVP and carrageenan (CAR) in different ratios were prepared by the ...

Serving as shape control agent, polyvinyl pyrrolidone (PVP) has been widely used in chemical synthesis of metal nanoparticles. However, the role of molecular weight (MW) of PVP has been rarely concerned. In this study, we show a facile method to control the shapes of silver nanocrystals using PVP with different MWs. PVPMW=8,000, PVPMW=29,000, PVPMW=40,000, and PVPMW=1,300,000 are compared in th...

OBJECTIVE Posteroventral pallidotomy (PVP) has proved to be an effective method for the treatment of Parkinson's disease. However, data on bilateral procedures are still limited. To assess the effects of bilateral globus pallidus (GPi) lesion and to compare it with a combination of unilateral GPi lesion plus contralateral GPi stimulation (PVP+PVS), an open blind randomised trial was designed. ...

polyvinylidene fluoride/polyvinylpyrrolidone (pvdf/pvp) hollow fiber membranes were fabricated by dry-jet wet-spinning process. the correlated effects of the air gap length and pvp concentration ((1) the air gap length effect at the low and high pvp concentration in the dope solutions, as well as (2) the effect of the pvp concentration at the same air gap length) on the cross-section structure ...

Here we report a product evaluation for a non-adherent, povidone-iodine (PVP-I) dressing, determining the clinical need for the product, performing a literature review, clinical evaluation and cost-analysis, and developing a recommendation. This evaluation included 20 patients who experienced dressing pain with the previous antimicrobial dressing. Two patients discontinued the evaluation and fo...

Photoselective vaporisation of the prostate (PVP) is an established treatment option for bladder outlet obstruction (BOO). PVP has demonstrated durable clinical efficacy equivalent to other endoscopic procedures at 5 years [1]. Furthermore, PVP has demonstrated superior haemostatic properties compared with other endoscopic treatments for Benign Prostatic Hyperplasia (BPH) [2]. Despite this many...

This work relies on the use of dip-coating at various withdrawal speeds to form nanocomposite films, with a detailed analysis influence mode deposition nanoparticle (NP) concentration in dried film. While polymer solutions one hand and colloidal suspensions NPs other have been separately studied by dip coating, their combination is far being simple superposition two separate behaviors. The form...

OBJECTIVES The aim of the study was to investigate the clearance of PVP-iodine applied as a gel or solution in periodontal pockets. METHODS Teeth of 12 subjects with at least eight periodontal pockets of ≥5 mm probing depth were isolated with a rubber dam to allow contamination-free access to the pockets. In each subject, three pockets were filled with PVP-iodine gel (10%) and three with PVP-...

One of the most important consequences of acute left ventricular dysfunction (LVD) is pulmonary edema resulting from a rise in pulmonary venous pressure (PVP). It is generally believed that the PVP rise is a direct hemodynamic consequence of LVD. While this paradigm seems plausible, especially if the LV is viewed as a sump pump, there is no specific evidence to support this simple explanation. ...

PURPOSE To perform a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing monopolar transurethral resection of the prostate (MTURP) and photoselective vaporization of the prostate (PVP) in order to provide the most up-to-date and reliable recommendations possible. MATERIALS AND METHODS Relevant RCTs were identified from electronic databases for meta-analysis of...