BACKGROUND Predicting the allergenicity of proteins is challenging. We considered the possibility that the properties of the intact protein that may alter the likelihood of being taken up by antigen presenting cells, may be useful adjuncts in predicting allergens and non-allergens in silico. It has been shown that negatively charged acidic proteins are preferentially processed by dendritic cell...

Bacteria may encounter a very wide variety of conditions in nature. These include changes in salinity, temperature, pH, and the presence of antibacterial molecules that have evolved either to kill them or impede their growth. In response, some bacteria have evolved modifications of their membrane lipids that improve their survival. Among these are amino acyl derivatives of phosphatidylglycerol ...

fundamentally, public services must be of high quality so as to satisfy the wants and needs of the beneficiaries. but it’s worrisome to discover that in uganda, public services provided are of poor quality due to unethical behaviors and wanting leadership. the purpose of this study is to show that transformational leadership can advance ethical culture to spur provision of quality services. a r...

one of the most dazzling events in the atmosphere is lightning. during updrafts in the life cycle of cumulus clouds, collision of graupels and ice crystals in the presence of liquid water results in vertical separation of electrical charges and lightning. there are four types of lightening depending on the location of discharge. the first type is cloud-to-ground lightning or fork lightning that...

BACKGROUND Describing the characteristics and patterns of suicidal behavior is an essential component in developing successful prevention efforts. The Data and Surveillance Task Force (DSTF) of the National Action Alliance for Suicide Prevention was charged with making recommendations for improving national data systems for public health surveillance of suicide-related problems, including suici...

Performance Assessment (PA) is the use of mathematical models to simulate the long-term behavior of engineered and geologic barriers in a nuclear waste repository; methods of uncertainty analysis are used to assess effects of parametric and conceptual uncertainties associated with the model system upon the uncertainty in outcomes of the simulation. PA is required by the U.S. Environmental Prote...

one of the features of democratic political systems is its accountability to respond their own responsibility. the media as a powerful element of civilization affecting public thoughts plays an important role in government responsiveness. to achieve this goal, the present study tries to investigate the effect of media on the improvement of the accountability of the government agencies. the stat...

Hospital palliative care programs in the United States are growing in number, scope, and sophistication. The nation's major public-private partnership organization charged with advancing the quality of health care, the National Quality Forum (NQF), developed A Framework for Preferred Practices for Palliative and Hospice Care Quality: A Consensus Report. This Framework establishes a set of 38 pr...