نتایج جستجو برای: ptm
تعداد نتایج: 1366 فیلتر نتایج به سال:
Abstract Wir quantifizieren den Fluss von Protamin (Ptm) durch CymA, einen passivem Membrankanal zur Aufnahme Cyclodextrin. Unter Verwendung eines Fluoreszenztests auf Reporterpaarbasis konnten wir Eintritt Ptm in CymA‐haltige Liposomen nachweisen. Die Kinetik des Ptm‐Eintrags war unabhängig seiner Konzentration, was darauf hindeutet, dass die Permeation CymA der geschwindigkeitsbestimmende Fak...
Experiments were performed to determine whether remodeling of the actin cytoskeleton contributes to arteriolar constriction. Mouse tail arterioles were mounted on cannulae in a myograph and superfused with buffer solution. The alpha1-adrenergic agonist phenylephrine (0.1-1 micromol/l) caused constriction that was unaffected by cytochalasin D (300 nmol/l) or latrunculin A (100 nmol/l), inhibitor...
Post-translational modifications (PTMs) provide an extensible framework for regulation of protein behavior beyond the diversity represented within the genome alone. While the rate of identification of PTMs has rapidly increased in recent years, our knowledge of PTM functionality encompasses less than 5% of this data. We previously developed SAPH-ire (Structural Analysis of PTM Hotspots) for the...
RATIONALE Cardiac resynchronization therapy (CRT) is an effective clinical treatment for heart failure patients with conduction delay, impaired contraction, and energetics. Our recent studies have revealed that mitochondrial posttranslational modifications (PTM) may contribute to its benefits, motivating the present study of the oxidative regulation of mitochondrial ATP synthase. OBJECTIVES W...
BACKGROUND The use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed to compare prophylactic radiotherapy with deferred radiotherapy (given only when a PTM developed) in a suitably powered trial. METHODS We did a multicentre, open-label, phase 3, randomised control...
Nitric oxide (NO) has been demonstrated as an essential regulator of several physiological processes in plants. The understanding of the molecular mechanism underlying its critical role constitutes a major field of research. NO can exert its biological function through different ways, such as the modulation of gene expression, the mobilization of second messengers, or interplays with protein ki...
AIMS The Medical Curriculum Munich (MeCuM) has been implemented since 2004 and was completely established in 2007. In this study the clinical part of MeCuM was evaluated with respect to retention of the knowledge in internal medicine (learning objectives of the 6th/7th semester). METHODS In summer of 2009 and winter of 2009/2010 1065 students participated in the Progress Test Medizin (PTM) fr...
Pass-Transistor Mapper (PTM), a logic synthesis tool speci cally designed for passtransistor based logic library that has only three basic cells, is reported. It exploits the close relationship between BDD representation of logic and the structure of pass-transistor logic cells to ensure e cient technology mapping. BDD variable order optimization is achieved through a genetic algorithm with dyn...
Although an all-ceramic restoration is increasingly in use in dentistry, a conventional metal ceramic restoration is still considered to be a gold standard. However, with increasing demand in esthetics and advances in ceramic technology, future of metal ceramic restoration has been less certain, necessitating additional qualities in terms of superior esthetics and easy fabrication. A ceramic-pr...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید