In rheumatic diseases, biomarkers may serve as surrogate endpoints for diagnosis, prognosis, disease activity, therapeutic response and disease outcome. In recent years a great effort has been made to identify useful tools to establish early diagnosis, prognosis and therapeutic response especially in rheumatoid arthritis (RA). In psoriatic arthritis (PsA) serological biomarkers have been freque...

in a prospective clinical trial, the incidence of scrotal tongue in psoriatic patients was studied. one hundred psoriatics and the same number of non-psoriatic individuals were evaluated for the incidence of fissured tongue, age, duration of illness, and clinical types of psoriasis. in this study 49 psoriatic patients (49%) and 28 non-psoriatic persons (28%) had fissured tongue. the most common...

BACKGROUND With expanding therapeutic possibilities for treatment of psoriatic arthritis (PsA) it will be increasingly important to determine residual disease and define when to adjust treatment. The rationale behind treatment decisions in current daily clinical practice and the relationship with residual disease activity has not been investigated. The aim of this study was to assess current cl...

Early diagnosis and treatment of psoriatic arthritis (PsA) are critical for achieving optimal control of the disease and preventing progression to joint destruction, functional disability, and reduced quality-of-life. The comorbidities associated with PsA, such as depression and cardiovascular events, should also be prevented, detected, and treated. These are realistic objectives because we now...

OBJECTIVES Moderate to severe psoriasis, once regarded as merely a skin disease, is today seen as an inflammatory systemic disease. The sex ratio of the prevalence of psoriasis is balanced. In recent years several reports have documented that men receive more systemic or UV treatment than women, and different hypotheses were made. In PsoReg, the national registry for systemic treatment of psori...

In a prospective clinical trial, the incidence of scrotal tongue in psoriatic patients was studied. One hundred psoriatics and the same number of non-psoriatic individuals were evaluated for the incidence of fissured tongue, age, duration of illness, and clinical types of psoriasis. In this study 49 psoriatic patients (49%) and 28 non-psoriatic persons (28%) had fissured tongue. The most c...

OBJECTIVE The purpose of this study was to compare mortality risks of patients with Charcot arthropathy with those of patients with diabetic foot ulcer and those of patients with diabetes alone (no ulcer or Charcot arthropathy). RESEARCH DESIGN AND METHODS A retrospective cohort of 1,050 patients with incident Charcot arthropathy in 2003 in a large health care system was compared with patient...

Sir, We read with interest the article by Of®dani et al. entitled ``Subclinical joint involvement in psoriasis: magnetic resonance imaging and X-ray ®ndings'' (1). Psoriatic arthritis (PA) is an in ̄ammatory arthropathy occurring in 5 ± 7% of patients with psoriasis. Several distinct pattern of PA are present, namely: oligoartriculer, arthritis mutilans, symmetric and asymmetric polyarthritis, a...

The protestant cemetery of Saint-Maurice as well as what remains of the Charenton Temple (1607-1686) are among the most recently excavated sites of the Val de Marne. The salvage excavation directed by J. Y. Dufour of Institut national de recherches archéologiques préventives (INRAP) in 2005, where a medical facility was built, was instrumental in flagging not only an important 17 th century pro...