Background Extensive studies have revealed an increased risk of major adverse cardiac outcomes in patients with severe psoriasis. However, some studies show conflicting results. Objective This study was conducted to assess the CV risk factors in psoriasis patients, and compare it with non-psoriatic patients. In addition, we evaluated if psoriasis is an independent CV risk factor, if its sever...

OBJECTIVE To determine the risk of chronic kidney disease in patients with psoriasis. DESIGN Population based cohort study and nested cross sectional study. SETTING Electronic medical records database based in United Kingdom. PARTICIPANTS Cohort study: patients with psoriasis aged 18-90 each matched to up to five patients without psoriasis based on age, practice, and time of visit. Nested...

Many studies have suggested that cardiovascular risk factors seem to be more common in patients with psoriasis than in the general population. In this study we aimed to determine the prevalence of cardiovascular risk factors in patients with chronic plaque psoriasis depending on the severity of disease. We conducted a prospective study in Braşov County (Romania) including 142 patients with chro...

Psoriasis vulgaris is a chronic inflammatory disease that classically affects skin and joints and is associated with numerous comorbidities. There are several clinical subtypes of psoriasis including the uncommon pustular variants, which are subdivided into generalized and localized forms. Generalized forms of pustular psoriasis include acute generalized pustular psoriasis, pustular psoriasis o...

BACKGROUND Psoriasis may significantly impair sexual function. Depression and organic factors appear to play a key role in this relation. However, beyond genital psoriasis, the importance of the disease's distribution patterns has not been considered. OBJECTIVES To research sexual function in psoriasis patients and investigate the roles of anxiety, depression and psoriasis' distribution patte...

Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored. The goal of this study was to evaluate known risk alleles of psoriasis for association with age of psoriasis onset in three well-defined case-only cohorts totaling 1,498 psoriasis patients. We selected 39 geneti...

Background: Psoriasis has been considered of late as dermatological disorder with systemic inflammation that could contribute to various systemic events. There are studies that have demonstrated increased Serum uric acid levels in patients with psoriasis and psoriatic arthritis. There have been no studies so far on Uric acid levels in relation to psoriasis and metabolic syndrome (MetS). Objecti...

Several tools have been introduced in clinical trials to quantify the severity and the response to a given therapeutic regimen of both psoriasis and psoriatic arthritis. Each method present specific advantages and limitations. Here we will discuss some of the most popular clinical outcome measures of both psoriasis (Psoriasis Severity Index, Physician Global Assessment, National Psoriasis Funda...

knowledge is of great importance; therefore it is very crucial to use an antifungal agent asadditional treatment for psoriasis in patients. this study was designed to evaluate thepresence of candida albicans and other species of candida in the saliva and skin of 50psoriatic patients. the result of this study was compared to the control group of 50healthy people. this research study was carried ...