Pseudoxanthoma elasticum (PXE) is a rare, inherited, multisystem disorder characterized by progressive calcification and fragmentation of elastic fibers. Typically, small, yellowish papules are located on the neck and flexural areas; however, localized acquired cutaneous PXE has been proposed as a non-heritable form of the disorder. We report a patient who had normal appearing skin on the chin ...

A patient with pseudoxanthoma elasticum presented in pulmonary oedema with restrictive left ventricular cardiomyopathy caused by calcified endocardial bands that were confirmed on echocardiography and at catheterisation. The bands were resected as far as possible and the involved mitral valve was replaced by a heterograft. A year later calcification of the heterograft forced its replacement by ...