Background and Objective: Burn wound infections caused by Pseudomonas aeruginosa exhibiting β-lactam antibiotic resistance are one of the greatest challenges of antimicrobial treatment. In this context, P. aeruginosa strains harboring resistance mechanisms, such as production of extended-spectrum beta-lactamases have the highest clinical impact no the management of burn wound infections. The ai...

background and objective: the opportunistic pathogen pseudomonas aeruginosa secrets a capsule-like polysaccharide called alginate which is important for evasion of host defenses, especially in patients with suppressed immunity. method of alginate determination has an important role in the study of microbial alginate. in this study, a novel method for alginate determination by highperformance li...

background : due to the importance of the metal zinc as an essential biological element with known toxic properties, and considering the widespread secondary infections caused by pseudomonas aeruginosa strains with resistance to antibiotics and disinfectants, the present study aimed at exploring the antimicrobial properties of the metal zinc in both clinical and environmental multiple drug resi...

conclusions the results of this study indicated that a decrease in oprd gene expression is an important mechanism of resistance in carbapenem resistant pseudomonas aeruginosa isolated from severe burn patients with secondary infection. results our study showed that 94.2% of the isolates were resistant to imipenem, 99.5% to meropenem, and all were resistant to ertapenem. the oprd gene expression...

background pseudomonas aeruginosa is a leading cause of infections especially in patients with weakened immune systems. this pathogen is intrinsically resistant to many antibacterial agents. objectives the aim of this study was to survey the antibiotic resistance pattern and frequency of bla oxa10 gene in carbapenemase producing p. aeruginosa isolated from patients in isfahan hospitals. materia...

PURPOSE To report the treatment of therapy-resistant Pseudomonas aeruginosa keratitis with topical piperacillin/tazobactam. METHODS Retrospective report of 3 cases. RESULTS Three patients with P. aeruginosa keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of keratitis occurred upon commencement of topical piperacillin/tazobactam. CONCLUSION Therapy-resistan...

bacteria is Pseudomonas aeruginosa (P. aeruginosa), which is usually associated with human nosocomial infections,sever opportunist infections, ventilated-associated pneumonia (VAP) andinfections in the lungs of patients suffering from cystic fibrosis (1, 5-7).P. aeruginosa is a one of main respiratory tract pathogen. Rapid colonization of biofilm-forming pathogenic bacteria as P. aeruginosa on ...

We demonstrated that a 2% suspension of Pseudomonas aeruginosa alginate completely blocked the diffusion of gentamicin and tobramycin, but not that of carbenicillin, illustrating how alginate production can help protect P. aeruginosa growing within alginate microcolonies in patients with cystic fibrosis (CF) from the effects of aminoglycosides. This aminoglycoside diffusion barrier was degraded...

Pseudomonas aeruginosa is frequently isolated in swimming pool settings. Nine recreational and rehabilitative swimming pools were monitored according to the local legislation. The presence of P. aeruginosa was correlated to chlorine concentration. The ability of the isolates to form a biofilm on plastic materials was also investigated. In 59.5% of the samples, microbial contamination exceeded t...