PURPOSE To report efficacy in our series of nodular recurrences in the post-surgical bed that underwent salvage low-dose-rate (LDR) brachytherapy. MATERIAL AND METHODS Patients with radical prostatectomy (RP) who had biochemical failure with nodular recurrence detected by DRE, ultrasound, and pelvic CT and then salvaged with LDR (125)I brachytherapy were included. Nodular recurrences were bio...

Objective: To evaluate the clinical efficacy of combination of intermittent androgen deprivation and I brachytherapy (BT) for the treatment of locally advanced prostate cancer. Method: A total of 31 patients with locally advanced prostate cance were treated with the Combination Of I Brachytherapy and Intermittent Androgen Deprivation. Bicalutamide 50 mg Qd and Goserelin 3.6 mg every 28 days wer...

Küçük hücreli prostat karsinomu (KHPK) oldukça nadir görülmekte olup, tüm kanserlerinin yaklaşık %1'ini oluşturur. Agresif seyirli olup tanı anında hastaların yarısı metastatik evrededir. KHPK, klasik adenokarsinomuyla kıyaslandığında akciğer ve karaciğer başta olmak üzere hızla gelişen viseral metastazlar, osteolitik kemik metastazları, beyin tutulumu paraneoplastik sendromlar gibi belirgin ol...

123 Background: Restaging with PET-CT in biochemical recurrent prostate cancer after prostatectomy shows a higher frequency of (false) negative cases compared to restaging after EBRT. It is uncertain if this reflects low volume of disease and/or low grade as biopsies fail to prove recurrent cancer in 50% of cases. We followed the clinical course of men with recurrent prostate cancer (PCa) after...

AIM To evaluate the toxicity of a hypofractionated schedule for primary radiotherapy (RT) of prostate cancer as well as the value of the nadir PSA (nPSA) and time to nadir PSA (tnPSA) as surrogate efficacy of treatment. MATERIAL AND METHODS Eighty patients underwent hypofractionated schedule by Helical Tomotherapy (HT). A dose of 70.2 Gy was administered in 27 daily fractions of 2.6 Gy. Acute...

In 1997, we resolved to survey UsToo members and other men known at that time to be taking PC-SPES, a Chinese herb combination that contains eight herbs: chrysanthemum, dyers woad, licorice, reishi, san-qi ginseng, rabdosia, saw palmetto, and baikal skullcap. The survey showed positive results, with respondents experiencing a decline in serum prostate specific antigen (PSA), most to the undetec...

Prostatic carcinoma has proven extremely difficult to establish as cell lines or xenografts. In this article, we describe a new series of prostate cancer xenografts propagated in athymic mice, designated LuCaP 23, developed from prostate metastases harvested at autopsy shortly after death. Tumor from three separate metastatic deposits was developed into three xenograft sublines: two from lymph ...

Long-term complete regression of prostate cancer (PCa) is a rare phenomenon. The current report presents the case of an advanced PCa patient with rare clinical features. Following the generation of a definitive diagnosis, the patient was administered with flutamide treatment (0.25 g flutamide) 3 times a day, for 5 consecutive years, prior to surgical castration. Following surgery, 3.75 mg enant...