It has been reported that 10-50% of patients with pruritus but no skin rash have an underlying systemic disease and up to 70% a psychiatric one. The aim of this retrospective study was to review the records of a large number of patients with chronic pruritus for concomitant diseases and treatment options. Medical records of 139 patients (52 males, 87 females) with chronic pruritus who visited t...

Opioids are a mainstay of treatment for pain worldwide. Pruritus, common side effect opioids, is patient dissatisfier that limits their use in many clinical settings. Both parenteral and neuraxial administration opioids frequently evoke pruritus. The ability to suppress while causing itch continues perplex clinicians researchers alike. Several mechanisms have been proposed explain how can give ...

Anogenital irritation is a fairly common complaint by women in a general practitioner's surgery. No age group is exempt, if nappy rash is included, but strictly speaking pruritus is itching or irritation rather than soreness. In this region pruritus is a particularly distressing complaint because to attempt to relieve it by scratching is socially unacceptable. For this reason, parents may consu...

Chronic pruritus is a common symptom and there is an urgent need to test new anti-pruritic substances in high-quality clinical trials. However, no widely accepted standardized and validated method for objectively measuring pruritus is yet available. A special interest group of the International Forum for the Study of Itch has been established to assess scoring methods and questionnaires for use...

Pruritus is the most frequently described symptom in dermatology and can significantly impair the patient's quality of life. In 10-50% of adults with persistent pruritus, it can be an important dermatologic clue for the presence of a significant underlying systemic disease such as renal insufficiency, cholestasis, hematologic disorder, or malignancy (Etter and Myers, 2002; Zirwas and Seraly, 20...

Chronic pruritus (> 6 weeks) can be caused by skin diseases and systemic diseases, including malignancies. It is a distressing symptom that requires a precise medical history, thorough physical examination, laboratory and radiological diagnostics. The interpretation of results may sometimes be difficult and may often reveal several pathological findings. This case report demonstrates prostate c...

In the past, several textbooks defined psoriasis as a non-pruritic dermatosis, but the most recent data in the literature emphasizes the high frequency of pruritus in psoriasis and its impact on the quality of life of patients with psoriasis. Aim of this study was to explore the sensory and affective dimensions of pruritus as well as to assess the impact of itch on quality of life and to evalua...

Pruritus (itching) is a common and distressing complaint after injury. The purpose of this study was to investigate self-reported postburn pruritus in a large, multisite cohort study of adult burn survivors. Descriptive statistics, general linear regression, and mixed model repeated measures analyses were employed to test statistical significance. Two cohorts of adult burn survivors were studie...

BACKGROUND Pruritus is one of the major features of lichen planus (LP); however, its pathogenesis remains largely unknown. Objective. The aim of our study was to analyze the role of IL-31 in the pathogenesis of pruritus in LP. MATERIALS AND METHODS The study group included 22 patients with LP. Control group consisted of 14 healthy volunteers. All subjects underwent thorough examination. Pruri...

Chronic itch is a common and distressing symptom that arises from a variety of skin conditions and systemic diseases. Despite this, there is no clinically based classification of pruritic diseases to assist in the diagnosis and cost-effective medical care of patients with pruritus. The proposed classification focuses on clinical signs and distinguishes between diseases with and without primary ...