protein protein interaction network analysis

Background and purpose: Interferon beta-1b recombinant protein is used for reducing the relapse rate and treatment in patients with Multiple sclerosis (MS). In this study, phylogenetic and in silico analysis of interferon beta-1b were conducted by servers and bioinformatics tools to predict its structural potential. Materials and methods: Physiological and physico-chemical characteristics of...

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Protein interaction and microRNA network analysis in osteoarthritis meniscal cells

Journal: :Genetics and Molecular Research 2013

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how hepatitis c virus leads to hepatocellular carcinoma: a network-based study

Journal: :hepatitis monthly 0

vahdat poortahmasebi hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, ir iran mansour poorebrahim department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, ir iran; department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, ir iran. tel: +98-9120192664 saeideh najafi department of microbiology, tonekabon branch, islamic azad university, tonekabon, ir iran seyed mohammad jazayeri hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, ir iran seyed moayed alavian middle east liver diseases (meld) center, tehran, ir iran seyed shahriar arab department of biophysics, faculty of biological sciences, tarbiat modares university, tehran, ir iran

conclusions our results revealed the possible crucial genes and mirnas involved in the initiation and progression of hcc cells infected with hcv. results based on the topological analysis of mirna-hubgene network, we identified the key hub mirnas. in order to identify the most important common sub-network, we aligned two ppi networks using netal tool. the c-jun gene was identified as the most i...

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