Hajime Sugiura and Susumu Hasegawa Department of Urology, Nagoya City University Medical School (Director: Prof. N. Oka) Since our original report of transrectal approach using television fluoloscopy for roentgenographic visualization of benign prostatic hyperplasia, we have continued to apply this technique to the cases of benign hyperplasia, carcinoma, inflammatory disease and normal conditio...

PURPOSE To determine the occurrence of incidental carcinoma of the prostate, its characteristics, and the risk factors for this diagnosis in a group of patients surgically treated for benign prostatic hyperplasia. METHODS The study comprised a retrospective analysis of 218 patients. After surgical treatment, patients with the finding of incidental carcinoma of the prostate were compared to th...

Epigenetic mechanisms permit the stable inheritance of cellular properties without changes in DNA sequence or amount. In prostate carcinoma, epigenetic mechanisms are essential for development and progression, complementing, amplifying and diversifying genetic alterations. DNA hypermethylation affects at least 30 individual genes, while repetitive sequences including retrotransposons and select...

• The use of immunohistochemistry for basal cell markers and AMACR for the diagnosis of limited adenocarcinoma of the prostate should be used as an adjunct to the H&E diagnosis as there is false positive and negative staining with these markers. • Examples of labeling of prostate adenocarcinoma with basal cell markers include: aberrant scattered HMWCK staining of cancer cells; rarely the retent...

Carcinoma of the prostate is a common condition and often spreads to bone. We describe the imaging findings in two patients with known carcinoma of the prostate who presented with visual disturbance (both had papilloedema on examination). MRI showed occipital bone metastases and superior sagittal sinus thrombosis. We suggest that MRI is the imaging modality of choice in patients suffering from ...

background: to analyze the dosimetric and radio biologic advantages between intensity modulated radiotherapy (imrt) and 3 dimensional conformal radiotherapy (3dcrt) and selection of optimal photon energy for imrt treatments. material and methods: 24 patients with localized prostate carcinoma were planned for 3dcrt and imrt techniques. radiation dose of 54 gy with 2 gy/fraction, was planned to p...

Prostate is of great clinical importance and ultrasonography is an ideal diagnostic aid. High frequency transrectal ultrasonography (TRUS) provides a remarkably detailed view of the prostate. This study is aimed at demonstrating the ultrasonographic changes in the human prostate disorders during successive physiological changes of growth. This was an observational study done in Regional cancer ...

Trans urethral resection of prostate (TURP) is the most frequently performed surgical treatment for patients diagnosed with benign prostate hyperplasia. This retrospective observational study was design to evaluate the occurrence and the characteristics of incidental prostate cancer (IPC), in patients underwent TURP for clinically benign disease. In histopathology of TURP specimens 14.9% showed...

Small cell prostate carcinoma (SCPC) has a clinical course and prognosis that is markedly different from that of common adenocarcinoma of the prostate. The patient in this case presented with fever of unknown origin, dyspnea, and near spinal cord compression. He was subsequently found to have widely metastatic high-grade neuroendocrine carcinoma of prostatic origin. This case emphasizes that de...

Intradural metastatic tumors are rarely reported in foramen magnum (FM), including cases of melanoma, pituitary carcinoma, thyroid carcinoma, and prostate carcinoma metastases. We report a 68-year-old male who presented with right-sided headache, progressive swallowing difficulty requiring gastrostomy tube and hoarseness over the course of 1 year. Images revealed a heterogeneous, contrast-enhan...