نتایج جستجو برای: proprotein convertase subtilisinkexin type 9
تعداد نتایج: 1753151 فیلتر نتایج به سال:
Journal:
:Baylor University Medical Center Proceedings
2017
Journal:
:Arteriosclerosis, Thrombosis, and Vascular Biology
2015
Journal:
:Clinical & Investigative Medicine
2017
Journal:
:Journal of Lipid Research
2007
Journal:
:Journal of the American College of Cardiology
2013
Journal:
:Pharmacological Reviews
2016
Journal:
:The Journal of biological chemistry
2008
Sanae Kourimate
Cédric Le May
Cédric Langhi
Anne Laure Jarnoux
Khadija Ouguerram
Yassine Zaïr
Patrick Nguyen
Michel Krempf
Bertrand Cariou
Philippe Costet
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with familial autosomal dominant hypercholesterolemia and is a natural inhibitor of the LDL receptor (LDLr). PCSK9 is degraded by other proprotein convertases: PC5/6A and furin. Both PCSK9 and the LDLr are up-regulated by the hypocholesterolemic statins. Thus, inhibitors or repressors of PCSK9 should amplify their beneficial ef...
Journal:
:The Korean Journal of Internal Medicine
2020
Journal:
:Scientific Reports
2017
Journal:
:Clinical Chemistry
2009
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