contraceptives. Significant increases in macroglobulin, transferrin, and IgG were found but albumin was unchanged. The purpose of the present experiment was to determine whether the oestrogen or progestogen component was responsible for these changes. Two groups of 14 healthy females were given either 50 mg oestrogen (mestranol) or 1 mg progestogen (ethynodiol diacetate) daily for three weeks. ...

I NCREASING the number of lambings per year offers an important potential in increasing the efficiency of the sheep industry. Much progress has been made in recent years in inducing pregnancy in the ewe during anestrus. In order to approach two lamb crops per year, either very early weaning will have to be practiced or fertility induced in lactating ewes. Two injections of PMS (pregnant mare se...

Thirty-two amenorrheic patients were treated with a tablet oral placebo preparation for a period varying from 30 to 180 days. Another 24 amenorrheic patients were also treated with a placebo administered i.m. for a period varying from 30 to 120 days. As a consequence of the treatment, 27 patients (48%) had menstrual bleedings. The progestogen withdrawal test responsive patients were more respon...

In a five-year analysis of an oral contraceptive trial by the Council for the Investigation of Fertility Control venous effects were the third most troublesome group of side-effects with both combined and sequential therapy. Vein complaints, leg cramps, and thrombophlebitis were significantly more frequent with the combined preparations that contained a relatively low dose of progestogen and a ...

Complete androgen insensitivity syndrome or testicular feminization is the most common form of male pseudohermaphrodism, caused by a failure receptor binding. Patient with genotype 46 XY, has female morphotype well developed external sexual organs. We report case two young patients aged 23 and 21 TF discovered during exploration primary amenorrhea. A bilateral orchiectomy was performed institut...

The understanding of the cause and treatment of premenstrual disorders is confused but it is essentially the result of cyclical ovarian activity, usually ovulation, and an effective treatment should be by suppressing ovulation. This can be done by an oral contraceptive but as these women are progestogen intolerant the symptoms may persist becoming constant rather than cyclical. Alternatively, t...

Reviewmethods MEDLINE, EMBASE/Excerpta Medica, and Cochrane Library (all to Jan 2015) and reference lists were searched for randomized controlled trials (RCTs). 47 RCTs (n = 8326) assessing 16 treatment classes (placebo, sham acupuncture, nonoral estrogen plus progestogen, oral estrogen plus progestogen, conjugated estrogens plus bazedoxifene, tibolone, raloxifene, selective serotonin reuptake ...