Many gene therapy approaches require specific, efficient gene delivery to cells in vivo. To target colorectal tumors we fused a single-chain variable fragment (scFv) directed against carcinoembryonic antigen (CEA) to the amphotropic murine leukemia virus envelope. A proline-rich hinge and matrix metalloprotease (MMP) cleavage site linked the two proteins. Following attachment to CEA, MMP cleava...

The EU emissions trading scheme (ETS) taking effect in 2005 covers CO2 emissions from specific large-scale industrial activities and combustion installations. A large number of existing and potential future combined heat and power (CHP) installations are subject to ETS and targeted for emissions reduction. CHP production is an important technology for efficient and clean provision of energy bec...

The widespread use of tracheal intubation and mechanical ventilation to support the critically ill patients increases the risk of development of tracheobronchitis and bronchopneumonia. This cross-sectional study was conducted with an aim to isolate and identify bacterial pathogens from tracheal aspirates producing extended-spectrum β -lactamase (ESBL), AmpC β -lactamase, and metallo- β -lactama...

In this paper, we develop an optimization model for the economic design of repetitive sampling plan in the presence of two markets. The process under consideration produces a product with a normally distributed quality characteristic with unknown mean and known variance. The quality characteristic has a lower specification limit. The quality of the product is controlled via lot-by-lot acceptanc...

Consumer and resource control of diversity in plant communities have long been treated as alternative hypotheses. However, experimental and theoretical evidence suggests that herbivores and nutrient resources interactively regulate the number and relative abundance of coexisting plant species. Experiments have yielded divergent and often contradictory responses within and among ecosystems, and ...

Abstract—Producer gas is a biomass derived gaseous fuel which is extensively used in internal combustion engines for power generation application. Unlike the conventional hydrocarbon fuels (Gasoline and Natural gas), the combustion properties of producer gas fuel are much different. Therefore, setting of optimal spark time for efficient engine operation is required. Owing to the fluctuating ten...