OBJECTIVES/HYPOTHESIS To determine the attitudes of otolaryngology residency program directors and chairpersons toward unmatched residency applicants, including whether a surgical internship or research year is preferred in considering repeat applicants. STUDY DESIGN Cross-sectional survey. METHODS Approval was obtained from the Colorado Multiple Institution Review Board. A 12-question Web-...

The emergence of urgent care centres in the United States signifies an innovative response to the demands-public, private and governmental-to control the rising costs of health care. What is immediately obvious to the practitioner, however, may or may not be quite so obvious to the consumer. Simply expressed, trade-offs must be made. In the accompanying article 'Urgent Care Centres', Drs Janiak...

Acyl-transfer catalysed by y-glutamyltranspeptidase from bovine kidney was studied using y-Land y-D-Glu-p-nitroanilide as the donor and GlyGly as the acceptor. The transfer of the y-Glu group to GlyGly was shown to be accompanied by transfer of the y-Glu group to water (hydrolysis). The results were compared with acyl-transfer catalysed by the representative serine protease, a-chymotrypsin. The...

Identifying the cancer cells-of-origin is of great interest, as it holds the potential to elucidate biologic mechanisms inherent in the normal cell state that have been co-opted to drive the oncogenic cell state. An emerging concept, proposed here, states that cancer stem cells, key players in cancer initiation and metastasis, arise when transit-amplifying cells with mutant genomes dedifferenti...

To explore the effect of PRECEDE-PROCEED model (the health professional’s ability to apply theories behavior) in education for young and middle-aged patients with lumbar disc herniation. Ninety herniation admitted our hospital from January 2020 October 2022 were selected divided into control group (n=45) observation according random number table. The received routine Chinese medicine education....

Early diagnosis and treatment are recognized strategies to reduce the long-term functional effects of chronic diseases, including psychotic disorders such as schizophrenia. Treatment may be delayed if youth, young adults and parents are not aware of the early signs and symptoms of psychosis, the need for early diagnosis and treatment and where and how to get help. This article describes the use...

Influenza vaccination of Health Care Workers (HCWs) is recommended by several health authorities worldwide aiming to prevent influenza, to reduce staff absenteeism due to illness and to protect vulnerable patient populations from the increased morbidity and mortality that influenza carries. However, despite recommendations and proven efficacy and cost effectiveness of influenza vaccine, vaccina...