The PRISM web server enables fast and accurate prediction of protein-protein interactions (PPIs). The prediction algorithm is knowledge-based. It combines structural similarity and accounts for evolutionary conservation in the template interfaces. The predicted models are stored in its repository. Given two protein structures, PRISM will provide a structural model of their complex if a matching...

The space-time prism has been widely used to model individual movements with respect to both space and time. It demarcates all locations that a mobile object can occupy given the origin and destination anchors, the earliest origin departure time, the latest destination arrival time, and the maximum allowed travel 1970, Lenntorp 1976). Although the prism boundary has been widely recognized and a...

Visuomotor prism adaptation has been found to induce a lateral bias of spatial attention in chronic hemispatial neglect patients. Here, two experiments were conducted to explore the effects of 10 degrees prism adaptation on visual search tasks and standard visual inattention tests. Baselines and intervention effects were measured on separate days for all patients. The first experiment explored ...

AIMS To assess the impact of two paediatric intensive care unit retrieval teams on the performance of three mortality risk scoring systems: pre-ICU PRISM, PIM, and PRISM II. METHODS A total of 928 critically ill children retrieved for intensive care from district general hospitals in the south east of England (crude mortality 7.8%) were studied. RESULTS Risk stratification was similar betwe...

To test the effect of double vision on postural stability, we measured postural stability by electric stabilometry before prism-wearing and immediately, 15, 30, and 60min after continuous prism-wearing with 6 prism diopters in total (a 3-prism-diopter prism placed with the base up in front of one eye and with the base down in front of the other eye) in 20 normal adult individuals with their eye...

This study was designed with the aim of comparing the performances of the pediatric risk of mortality (PRISM), pediatric index of mortality (PIM), and revised version pediatric index of mortality 2 (PIM2) models in a pediatric intensive care unit (PICU) in China.A total of 852 critically ill pediatric patients were recruited in the study between January 1 and December 31, 2014. The variables re...

To avoid some of the limitations of studying soft-bed processes through boreholes, a prism of simulated till (1.8m 1.6m 0.45m) with extensive instrumentation was constructed in a trough blasted in the rock bed of Engabreen, a temperate glacier in Norway. Tunnels there provide access to the bed beneath 213m of ice. Pore-water pressure was regulated in the prism by pumping water to it. During exp...

Unilateral spatial neglect involves a failure to report or orient to stimuli in the contralesional (left) space due to right brain damage, with severe handicap in everyday activities and poor rehabilitation outcome. Because behavioral studies suggest that prism adaptation may reduce spatial neglect, we investigated the neural mechanisms underlying prism effects on visuo-spatial processing in ne...

Visuomotor adaptation to a prism-induced lateral displacement of the visual field induces mild perceptual biases in healthy individuals and improves symptoms of unilateral neglect. The present study employed a speeded visual search task to test the hypothesis that prism adaptation induces an adaptive redistribution of selective spatial attention. In Experiment 1, 32 neurologically healthy, righ...

This paper presents a knowledge engineering tool, called PRISM, to model collective behaviors of real-time IoT systems. PRISM is developed on the ADOxx Meta-Modeling Platform, in order to implement the new notion of a domain engineering method, known as behavior ontology. In PRISM, the ontology can be constructed as follows: 1) All the collective behaviors for a domain are defined from active o...