Background: The reel impact of malignant bone tumors in adults seems unclear in Black Africa. Aim: The aim of this study is to determine the epidemiological and the semiological profile of malignant bone tumors in rheumatology inpatients at Hospital University Center Sylvanus Olympio in Lome. Methods: It was a retrospective study of recorded cases conducted over a period of 19 years in the rheu...

introduction: hydatid disease caused by larval stage of echinococcus has been recognized endemically in many countries. liver and lungs are the most commonly affected organs. involvement of the head and neck region is rare and bony erosion due to hydatidosis is even rarer. case report: we report a case of a 17-year-old girl from a poor socio-economic background who presented with a right sided ...

canal tumors and, most commonly, metastases. The most common primary malignant bone tumor is chordoma, and the second most common is giant cell tumor. The presence of multiple lesions involving the sacrum and other bones suggests metastasis or multiple myeloma. Although the imaging findings of sacral tumors are nonspecific, a patient’s age and sex, and specific findings such as calcification or...

A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. Plain digital radiograp...

Positron emission tomography (PET) using [ 18 F]fluorodeoxyglucose (FDG) is a useful modality to examine many kinds of tumors, including primary bone tumors. Malignant bone tumors show higher FDG accumulation than benign tumors and earlier reports mention that FDG-PET can differentiate malignancy from benignancy; however, some benign bone tumors present with high FDG accumulation, which increas...

The receptor-activator of nuclear kappaB ligand (RANKL) signaling pathway plays an important role in the regulation of bone growth and mediates the formation and activation of osteoclasts. Osteoclasts are involved in significant bone resorption and destruction. Denosumab is a fully human monoclonal antibody against RANKL that specifically inhibits osteoclast differentiation and bone resorption....

Background: About half of all brain tumors are primary, and the remainder are metastatic. Tumors of the nervous system have unique characteristics that set them apart from neoplastic processes elsewhere in the body. The World Health Organization (WHO) has classified central nervous system (CNS) tumors as grades I to IV in increasing order of malignancy. The goal of this study was to follow the...

We aim to review the imaging appearance of primary bony tumors of the spine and simulating lesions. Benign bone tumors commonly appear as well-circumscribed, slow-growing lesions with a calcified or sclerotic matrix. Malignancy is often aggressive permeative lesions with bone destruction, cortical invasion and associated soft-tissue mass. CT is an excellent imaging modality for characterization...